Aim: To evaluate the impact of socioeconomic factors (SEFs) on survival of renal cell carcinoma (RCC) patients. Materials & methods: RCC patients diagnosed between 2007 and 2015 were collected from the SEER database. The crude and multivariate Cox regression analysis was used to identify the independent prognostic factors and quantity the mortality risks for overall survival (OS). Results: Three SEFs including marital status, insurance status and median household income were identified as prognostic factors for OS. SEF-stage was built based on the three SEFs. Moreover, the SEF-stage 1 had superior OS than SEF-stage 2 within the respective American Joint Committee on Cancer stages. Conclusion: The SEF-stage was an independently prognostic factor for OS in RCC. Incorporation of SEF-stage into the American Joint Committee on Cancer staging system might be beneficial for better survival prediction and clinical management. However, further studies were needed to validate these findings in other populations.
Future oncology (London, England). 2019 Jun 26 [Epub ahead of print]
Shi-Long Zhang, Zheng-Yan Zhang, Ze-Juan Liu, Wen-Rong Wang, Zhan-Ming Li, Bing Han, Xin Wang, Li-Shun Wang
Institute of Fudan-Minhang Academic Health System, Minhang Branch, Zhongshan Hospital, Fudan University, Shanghai 201199, PR China., Department of Pharmacology, Capital Medical University, Beijing 100069, PR China., College of Physical Education, Shandong Normal University, Jinan 250014, PR China., Department of Acupuncture & Moxibustion, Central Hospital of Shanghai Xuhui District, Shanghai 200031, PR China.