Partial nephrectomy (PN) is the standard treatment for small and localized kidney tumours (cT1). One of the controversial aspects regarding this technique is the management of affected/positive resection margins. We present the long-term oncological results in patients with PSM after PN managed conservatively.
There were 207 PN performed in our centre between 1990 and 2011. 17 patients presented PSM. 2 patients were excluded from the study due to completion nephrectomy afterwards. Follow-up was was done with abdominal contrast-enhanced computed tomography every 6 months for the first 2 years and subsequently, once a year. Cancer-specific survival and disease-free survival were calculated with the Kaplan-Meier method.
The median age was 62 years (RIQ: 55-71) and the mean tumour size was 34.8 (10-77) mm. Histopathological results were: 6 (40%) clear cell RCC, 4 (26.7%) papillary, 3 (20%) chromophobe and 2 (13.3%) oncocytic. The pathologic stages were: 11 (73.3%) pT1a, 1 (6.7%) pT1b and 3 (20%) pT3a. The median follow-up was 84 months (IQR 72-120). 2 patients had metastatic recurrence and this was the cause of death. The first one had recurrence at 112 months and the second one at 59. 5-year CSS and RFS were 87.5% and 93.3% respectively.
In our experience, patients with PSM after PN can be managed conservatively with satisfactory long-term oncological outcomes.
Actas urologicas espanolas. 2019 Jun 03 [Epub ahead of print]
J J Fernández-Concha Schwalb, J I Pérez Reggeti, M A López Costea, X Bonet Puntí, H Ramos Reina, F Vigués Julia
Servicio de Urología, Hospital Universitario de Bellvitge, Barcelona, España. Electronic address: ., Servicio de Urología, Hospital Universitario de Bellvitge, Barcelona, España.