(UroToday.com) For the past three decades or more, transrectal ultrasound-guided biopsy has been considered the standard diagnostic approach for the detection of prostate cancer. In the past few years, driven in large part by concerns regarding post-biopsy sepsis in patients undergoing TRUS procedures, transperineal biopsy has been increasingly utilized with equivalent cancer detection rate compared to TRUS biopsy, however patient experience remains unknown. In a moderated poster presentation at the American Urologic Association Virtual Annual Meeting, Stephanie Ferrante and colleagues presented results of their study assessing the patient experience with in-office transperineal biopsy under local anesthesia within the Michigan Urological Surgery Improvement Collaborative (MUSIC).