Protective Effects of Metformin against Biochemical Failure Following Radical Prostatectomy or Radiation Therapy in Localized Prostate Cancer.

To assess the impact of metformin on biochemical failure (BF) in localized prostate cancers (PC) treated with radical prostatectomy (RP) or radiation therapy (RT).

1,449 patients undergoing RP (n=1338, 92.