To assess the relationship between the volume of the index lesion (IL) measured at mpMRI (MRIvol) and at radical prostatectomy (RPvol), stratifying it according to PI-RADS score.
We identified 332 men with a positive mpMRI (single lesion with PI-RADS≥3) who underwent systematic plus targeted biopsy and subsequent RP at two tertiary referral centres between 2013 and 2018.