Alicia Morgans: Hi, this is Alicia Morgans, GU Medical Oncologist and Associate Professor of Medicine at Northwestern University, and I am so excited to have here with me today, a friend and colleague, Dr. Petros Grivas who is an Associate Professor of Medicine and a GU Medical Oncologist at the University of Washington. Thank you so […]
The therapeutic landscape of metastatic castration-resistant prostate cancer (mCRPC) has substantially evolved over the last decade. Nonetheless, a better understanding of bone-targeted agents (BTAs) action in mCRPC remains an unmet need.
Aim: Bladder cancer (BC) is one of the most common malignancies with poor prognosis. We aimed to identify a genetic signature for predicting the prognosis of BC. Materials & methods: Kaplan-Meier survival and Cox regression analyses were used to construct a prognostic signature using data from The Cancer Genome Atlas.
Testicular germ cell tumors (TGCTs) are heterogeneous neoplasms mostly affecting young-adult men. Despite high survival rates, some patients with disseminated disease acquire cisplatin resistance, entailing the need for less toxic therapies.
Penile cancer is a rare type of urological cancer. Predisposing factors include phimosis, poor hygiene, and smoking. Circumcision in early childhood has been shown to be protective against penile cancer.
{{header-clinical-trials-navigation}} A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Prostate Specific Membrane Antigen Half-life Extended Bispecific T-cell Engager AMG 160 in Subjects With Metastatic Castration-resistant Prostate Cancer Condition: Metastatic Castration-resistant Prostate Cancer, Prostate Cancer Study Type: Interventional Clinical Trials Identifier NCT 8-digits: NCT03792841 Sponsor: Amgen Phase: Phase 1 Eligibility: Age: minimum […]
Introduction: Management of the distal ureter during laparoscopic nephroureterectomy (LNU) for upper tract urothelial carcinoma (UTUC) is controversial.
The coronavirus disease 2019 (COVID-19) pandemic has become a public health emergency, affecting frail populations including cancer patients. This poses the question as to whether cancer treatments can be postponed or modified without compromising their efficacy, especially for highly curable cancers such as germ cell tumors (GCTs).
To evaluate the diagnostic accuracy of multiparametric magnetic resonance imaging in the detection of prostate cancer, according to Prostate Imaging Reporting and Data System, and the usefulness of combining clinical parameters to improve patients’ risk assessment.
N-α-Acetyltransferase 10 protein (Naa10p) was reported to be an oncoprotein in androgen-dependent prostate cancer (PCa; ADPC) through binding and increasing transcriptional activity of the androgen receptor (AR).
