In an effort to expedite the publication of articles pandemic, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing.
The gold standard therapy for localized clear cell renal cell carcinoma (ccRCC) is surgery while metastatic ccRCCs are treated with systemic therapies. Immune checkpoint and tyrosine kinase inhibition are the main therapeutic strategies for metastatic ccRCCs. They have substantially improved the prognosis of patients with metastatic ccRCC. However, a substantial number of patients never respond […]
Prior studies have documented that disparities exist in prostate cancer incidence, treatment, and outcomes among racial and ethnic minority groups. The recommendation for germline testing for a large proportion of men with prostate cancer has further exacerbated disparities in diverse patient populations. As genetic testing recommendations from National Comprehensive Cancer Network and other professional societies […]
To investigate and compare the effectiveness of active surveillance versus post-surgical active treatment, in patients with testicular germ cells tumor (TGCT). We retrospectively analyzed 52 patients who underwent surgery for TGCT from January 2009 to December 2014.
CD8+ T cells, vital effectors pertaining to adaptive immunity, display close relationships to the immunization responses to kill tumor cells. Understanding the effect exerted by tumor infiltration CD8+ T cells in papillary renal cell carcinoma (papRCC) is critical for assessing the prognosis process and responses to immunization therapy in cases with this disease.
We aimed to compare the outcomes of open vs robotic partial nephrectomy (PN), focusing on predictors of Trifecta failure in patients with highly complex renal masses. We queried the prospectively collected database from the SIB International Consortium, including 507 consecutive patients with cT1-2N0M0 renal masses treated at 16 high-volume referral centres, to select those with […]
The classical pathway for the therapy of low- to intermediate-risk localized prostate cancer is radical prostatectomy or radiation therapy, which has shown a high incidence of complications, including erectile dysfunction, urinary incontinence, and bowel injury.
To describe the establishment of a national prostate cancer clinical quality registry (PCOR-NZ) within the New Zealand healthcare system and discuss the challenges encountered and achievements obtained during its development.
Advances in high-dose-rate brachytherapy to treat prostate cancer hinge on improved accuracy in navigation and targeting while optimizing a streamlined workflow. Multimodal image registration and electromagnetic (EM) tracking are two technologies integrated into a prototype system in the early phase of clinical evaluation.
The underlying premise of prostate cancer Active Surveillance (AS) is that cancers likely to metastasize will be recognized and eliminated before cancer-related disease can ensue. Our study was designed to determine the prostate cancer upgrading rate when biopsy guided by magnetic resonance imaging (MRGBx) is used before entry and during AS.
