SUO 2021: PSMA Imaging and Outcome Following Dose-Intense PSMA-Targeted Radionuclide Therapy in Men with PSMA-Unselected, Pre-Treated, Metastatic Castration-Resistant Prostate Cancer

(UroToday.com) PSMA-targeted radionuclide therapy (TRT) is one of the most promising investigational therapies in prostate cancer currently. In the phase II TheraP trial and the phase III VISION trial, 177-lutetium-PSMA-617 has demonstrated better outcomes compared to the current standard of care treatment options for patients who have received many lines of therapy for metastatic castration resistant […]

SUO 2021: Diagnostic Performance of Piflufolastat F 18-PET/CT in Men with Biochemical Recurrence of Prostate Cancer after Definitive Treatment: A CONDOR Study Subanalysis

(UroToday.com) Prostate-specific membrane antigen (PSMA)-targeted imaging has rapidly gained interest and utilization in patients with prostate cancer. Recently, two approaches (68-Gallium and Piflufolastat F-18 [PYLARIFY, previously known as 18F-DCFPyL]) have gained FDA approval for prostate cancer patients with suspected recurrence based on elevated PSA. This is driven by a proven ability to better localize and determine […]

SUO 2021: The Future of Adjuvant Therapy for High-Risk Non-Metastatic Renal Cell Carcinoma

(UroToday.com) The Society of Urologic Oncology (SUO) 2021 annual meeting in Orlando, FL hosted a thought-provoking presentation by Dr. Pavlos Msaouel, MD, Ph.D. regarding the future of adjuvant therapy for high-risk non-metastatic renal cell carcinoma (RCC). Dr. Msaouel began his talk by presenting the seminal data from KEYNOTE-564 evaluating adjuvant pembrolizumab (KEYTRUDA ®) after nephrectomy […]

SUO 2021: Updates on the InPACT Trial

(UroToday.com) The Society of Urologic Oncology (SUO) annual winter meeting included a penile cancer session and a presentation by Dr. Juanita Crook discussing updates of the global InPACT trial. Penile cancer is rare and evidence to establish practice standards is limited. There is suggestion of benefit with neoadjuvant chemotherapy, as well as chemo-radiation being effective for […]

Phase III Investigational Trial of NUBEQA® (darolutamide) in Combination with Docetaxel and Androgen Deprivation Therapy (ADT) Meets Primary Endpoint of Significantly Increasing Overall Survival (OS) in Patients with mHSPC

Phase III ARASENS trial meets primary endpoint of overall survival for NUBEQA in combination with docetaxel and androgen deprivation therapy (ADT) versus docetaxel and ADT, a standard of care in men with metastatic hormone-sensitive prostate cancer (mHSPC) Bayer plans to present these pivotal data at a forthcoming scientific congress and discuss them with health authorities […]

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