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Clear-cell renal cell carcinoma (ccRCC) is one of the most common malignancies in humans and is usually associated with poor outcomes. Cancers are considered to be genetic diseases. Therefore, a better understanding of genetic alterations that are related to disease progression or poor prognosis can help to more precisely identify high-risk patients and treat them […]

This study aimed to evaluate the likelihood of progression to chronic kidney disease (CKD) in a cohort of geriatric Asian patients aged over 65 years who underwent either partial nephrectomy (PN) or radical nephrectomy (RN) for localised pT1 kidney tumours. Geriatric patients aged over 65 years who underwent PN or RN for localised kidney mass […]

Testicular germ-cell tumors represent the most common solid neoplasms among young men aged 20-40 yr. Owing to interdisciplinary management and high chemosensitivity, cure rates are high even among patients with poor risk. Although the diagnostic and therapeutic approaches for organ-confined disease and low-volume and high-volume metastatic disease are well standardized and reported in numerous national […]

PSMA-based 18F-DCFPyL PET/CT and PET/MRI Pilot Studies in Prostate Cancer Condition: Prostate Cancer, Prostate Neoplasm Intervention: Drug: 18F-DCFPyL PET Purpose: The overall goal of this research is to validate and develop a non-invasive imaging biomarker of prostate cancer detection, progression, and recurrence. Development of such a biomarker may be useful to differentiate indolent from aggressive […]

A Pilot Feasibility Study of Sipuleucel-T vs. Sipuleucel-T and Low-protein Diet in Patients With Metastatic Castrate-resistant Prostate Cancer (CRPC) Condition: Prostate Cancer Recurrent Intervention: Other: Low protein diet Other: Control protein diet Purpose: This is a single-center, randomized, open-label study to assess the feasibility of a low-protein diet intervention in patients with metastatic castrate-resistant prostate […]

Phase II Trial of Combination Immunotherapy in Biochemically Recurrent Prostate Cancer Condition: Prostate Cancer Intervention: Biological: PROSTVAC-V Biological: PROSTVAC-F Drug: MSB0011359C (M7824) Biological: CV301 Purpose: Background: Some people with prostate cancer have a rise in prostate-specific antigen (PSA). This can happen even after treatments like radiation and surgery. Androgen deprivation therapy (ADT) drugs and close […]

Abu Dhabi, United Arab Emirates (UroToday.com) In this session, Dr. Panagiotis Mourmouris and Dr. Evangelos Liatsikos debated the pros and cons of disposable single-use versus reusable multi-use ureteroscopes. Dr. Liatsikos, who was in favor of reusable scopes, began the debate by introducing the four categories every ureteroscope should satisfy: small caliber, good visualization, high deflection, and […]