Prospective Cohort-study for Evaluation of Clinical Outcome of Robot-assisted Cystectomy With Intracorporeal Reconstruction of Urinary Diversion

{{header-clinical-trials-navigation}} Prospective Cohort-study for Evaluation of Clinical Outcome of Robot-assisted Cystectomy With Intracorporeal Reconstruction of Urinary Diversion Condition: Urothelial Carcinoma, Cystectomy, Urinary Diversion, Complication of Surgical Procedure, Complication, Postoperative, Neobladder, Ileal Conduit, Robotic Surgical Procedures Intervention: Procedure: robot-assisted cystectomy Purpose: Continous evaluation of clinical and oncologic outcome of robot-assisted cystectomy with intracorporeal reconstruction of urinary […]

SIU 2019: Use of Molecular Biomarkers in Screening

Athens, Greece (UroToday.com) The objective of this talk given by Dr. Derya Tilki was to review the diagnostic biomarkers in the pre-biopsy setting of prostate cancer and to describe their cost-effectiveness. The ideal biomarkers in the pre-biopsy setting should be able to increase the probability of achieving a positive biopsy. Unfortunately, the positive predictive value of the […]

SIU 2019: Prostate Cancer Screening 2019: Doing It Right

Athens, Greece (UroToday.com) Dr. Laurence Klotz initiated this session on prostate cancer screening. According to Dr. Klotz, there are several problems with the current paradigm with PSA and systematic biopsy: PSA thresholds are too confusing for primary care physicians with no consensus at sight Overdiagnosis of insignificant cancer is a real problem Pathologic miss of significant cancer […]

SIU 2019: PET vs. MRI Directed Prostate Biopsy

Athens, Greece (Urotoday.com) In this talk, Dr. Izquierdo discussed the role of imaging in PSA only recurrence and local recurrences of prostate cancer in general. There are currently many modalities that have been used in the past and currently being used for imaging in the setting of PSA only recurrence. These include bone and conventional CT […]

Prospective multicentre study using high intensity focused ultrasound (HIFU) for the focal treatment of prostate cancer: Safety outcomes and complications.

To investigate focal therapy using High Intensity Focused Ultrasound (HIFU) for the treatment of localized prostate cancer (CaP), we analyzed the safety and complications of this procedure. Patients (pts) eligible for this multicenter prospective cohort study suffered from low to intermediate risk localized CaP with no prior treatment. After tumor identification on multiparametric MRI and […]

MRI-Fusion Targeted vs. Systematic Prostate Biopsy-How Does the Biopsy Technique Affect Gleason Grade Concordance and Upgrading After Radical Prostatectomy?

Introduction: MRI-targeted biopsy (TB) increases overall prostate-cancer (PCa) detection-rates and decreases the risk of insignificant PCa detection. However, the impact of these findings on the definite pathology after radical prostatectomy (RP) is under debate. Materials and Methods: Between 01/2014 and 12/2018, 366 patients undergoing prostate biopsy and RP were retrospectively analyzed. The correlation between biopsy […]

Risk of Gleason Score 3 + 4 = 7 prostate cancer upgrading at radical prostatectomy is significantly reduced by target biopsy compared to standard biopsy technique.

To evaluate if multiparametric magnetic resonance (mpMRI)- transrectal ultrasound (TRUS) fusion targeted biopsy (TBx) versus untargeted standard biopsy (SBx) may decrease the rate of pathological upgrading of Gleason score (GS) 3+4 prostate cancer (PCa) at radical prostatectomy (RP). We also evaluated the impact of percent pattern 4 and cribriform glands at biopsy in the risk […]

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