SIU 2019: Debate – Chemotherapy is Better than Immunotherapy as Neoadjuvant Therapy for Muscle Invasive Bladder Cancer

Athens, Greece (UroToday.com) Dr. Roland Seiler presented after Dr. Andrea Necchi, supporting the role of chemotherapy in the neoadjuvant setting of treating muscle invasive bladder cancer (MIBC), as opposed to immunotherapy. Radical cystectomy is the gold standard for the treatment of MIBC. Ways of improving the prognosis of patients undergoing radical cystectomy include perfecting the technique […]

SIU 2019: High Intensity Focused Ultrasound

Athens, Greece (Urotoday.com) Focal therapy can be defined as treatment of a specific focus (targeted ablation or limited defined region -quadrant-ablation or hemi-ablation). This discussion focused on high-intensity focused ultrasound (HIFU) modality. This entails ultrasound waves delivered transrectally from a spherical transducer. The high-intensity waves converge to a focal point and cause hyperthermia and damage […]

SIU 2019: Debate – Immunotherapy is Better than Chemotherapy as Neoadjuvant Therapy for Muscle-Invasive Bladder Cancer

Athens, Greece (UroToday.com) Dr. Andrea Necchi began the debate in this session supporting the role of immunotherapy over chemotherapy as neoadjuvant therapy for muscle-invasive bladder cancer (MIBC). According to the EAU guidelines, neoadjuvant immunotherapy to patients should only be given in the setting of a clinical trial, while chemotherapy is recommended as the standard of […]

SIU 2019: Focal Cryoablation for Prostate Cancer

Athens, Greece (UroToday.com) Cryoablation involves freezing of the targeted prostate tissue in two cycles, reaching minus 40 degrees Celsius, with the following histological changes: Protein denaturation Direct rupture of cell membranes by crystal formation Vascular stasis and secondary microthrombi formation Ischemic cell death Coagulative necrosis Ten-year data of whole-gland cryoablation in 370 patients with a follow-up […]

Magnetic resonance imaging findings of traumatic bulbar urethral stricture help estimate repair complexity.

To evaluate the magnetic resonance imaging (MRI) findings of traumatic bulbar stricture and to evaluate their ability to estimate repair complexity. Eighty-nine men with traumatic bulbar stricture who underwent urethrography and MRI at least 3 months post-injury and subsequent excision and primary anastomosis were retrospectively analyzed. The associations of MRI findings, including continuity of the […]

Multicriteria Decision Analysis Applied to the Clinical Use of Pharmacotherapy for Overactive Bladder Symptom Complex.

The nonspecific storage symptom complex overactive bladder (OAB) is an important clinical condition in functional urology. Until recently, pharmacological therapy comprised antimuscarinic drugs, but more recently beta 3 agonists have added to the available agents. Traditional reporting of efficacy and safety of these agents relies upon regulatory placebo-controlled studies. There remains no head-to-head comparison of […]

Single-use Versus Multi-use Catheters: Pro Single-use Catheters.

Currently there is neither a regulatory foundation nor evidence-based medicine available to recommend reuse or multiple use of catheters for intermittent catheterization. High-level evidence from studies comparing the effect of reuse/multiple use versus single use on symptomatic urinary tract infection and urethral injury is still missing. European urology focus. 2019 Oct 15 [Epub ahead of […]

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