IBCN 2019: Molecular Characterization of Normal Ureteric Urothelium for More Meaningful Comparisons with Bladder Urothelium

Aarhus, Denmark (UroToday.com) Dr. Andrew Mason began this session by discussing their efforts at the University of York to molecularly characterize normal ureteric urothelium, in order to permit more meaningful comparisons with bladder urothelium. Donor-matched bladder and ureteric urothelial cells were obtained from five patients undergoing ureteral reimplantation for non-oncologic purposes, and these cells were cultured […]

IBCN 2019: The Synergistic Potential of BCG and STING Pathway Activators to Improve Response of Non-Muscle Invasive Bladder Cancer

Aarhus, Denmark (UroToday.com) Dr. Madhuri Koti of Queen’s University in Kingston, Canada presented data investigating the synergistic potential of Bacillus Calmette-Guerin (BCG) and STING pathway activators to improve the response of non-muscle invasive bladder cancer patients. The STING pathway, or “stimulator of interferon genes” pathway, plays an important role in induction of chemokines. STING agonists […]

IBCN 2019: Advanced Pathologic T1 Substaging to Improve the Identification of High-Risk Non-muscle Invasive Bladder Cancer Patients at Risk for BCG-Failure

Aarhus, Denmark (UroToday.com) Dr. FC De Jong of the Erasmus MC Cancer Institute in Rotterdam discussed his group’s efforts in performing advanced pathologic T1 sub staging to improve the identification of high-risk non-muscle invasive bladder cancer patients who may be at risk for Bacillus Calmette-Guerin (BCG)-failure. Patients treated with TURBT and BCG between 2000 and […]

IBCN 2019: An Update to the UROMOL Non-Muscle Invasive Bladder Cancer Classification

Aarhus, Denmark (UroToday.com) Sia Lindskrog and Frederik Prip presented an update to the UROMOL Non-Muscle Invasive Bladder Cancer (NMIBC) classification. Previously, three major molecular subtypes were identified. With an updated cohort of 537 patients with non-muscle invasive disease, multiplexed immunofluorescence was performed on a subset of these tumors to identify T helper cells, cytotoxic T […]

Management of Nocturia and Nocturnal Polyuria.

Nocturnal polyuria (NP), characterized by overproduction of urine at night (greater than 20-33% of total 24-hour urine volume depending on age), is a major contributing factor in most nocturia cases. Nocturia can be caused by intake, urological, nephrological, hormonal, sleep, and cardiovascular factors. It is therefore important to accurately diagnose both the type of nocturia […]

The Economic Burden of Nocturia on the U.S. Health Care System and Society: A National Health and Nutrition Examination Survey Analysis.

Nocturia, characterized as waking during the main sleep period to urinate, is a common condition. Persistent nocturia results in sleep fragmentation with deleterious effects on health and well-being. Yet, there are limited data on the economic burden of nocturia in the United States. To assess the association of nocturia with health care resource utilization (HRU), […]

Friction underwear for ease of pulling down in elderly patients with overactive bladder: A prospective randomized control trial.

Friction underwear was developed by adding small silicon dots in front of the underwear to decrease the time for pulling down underwear in elderly patients with urge incontinence. We studied about the effects of the friction underwear for elderly overactive bladder (OAB) patients. Male patients over 60 years of age diagnosed with OAB were prospectively […]

Cost analysis of removing pediatric ureteral stents with and without a retrieval string.

Indwelling ureteral stents are commonly placed in urologic surgeries where optimal urinary drainage is necessary. In the pediatric population, removing a stent without retrieval string (SWOS) requires a secondary operation and additional anesthetic exposure. Although these burdens can be mitigated through the placement of a stent with retrieval string (SWS), fears of complications may prevent widespread […]

Pelvic floor rehabilitation in children with functional LUTD: does it improve outcome?

If children do not experience satisfactory relief of lower urinary tract dysfunction (LUTD) complaints after standard urotherapy is provided, other treatment options need to be explored. To date, little is known about the clinical value of pelvic floor rehabilitation in the treatment of functional voiding disorders. Therefore, we compared pelvic floor rehabilitation by biofeedback with […]

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