Latest News

High Dose Rate Partial Prostate Brachytherapy as Salvage Treatment for Local Failures After Previous External Beam Radiotherapy Condition: Recurrent Prostate Cancer Intervention: Radiation: HDR partial prostate brachytherapy Purpose: A dose-response relationship for radiation in the management of prostate cancer is well established. Local recurrence of prostate cancer after external beam radiotherapy occurs in at least […]

Phase I Trial of Image Guided Focally Dose Escalated Prostate SBRT for Locally Recurrent Prostate Cancer After Prior Radiotherapy Condition: Prostate Cancer, Prosatatic Neoplasm Intervention: Drug: 18F-DCFPyL Radiation: Tumor Irradiation Radiation: Prostate radiation + tumor boost irradiation Purpose: Background: Prostate cancer is the second leading cause of cancer death in U.S. men. Radiation is an […]

A Pilot Study Of Intermittent Androgen Deprivation Therapy Adapted To Serum Testosterone And PSA Levels For Stage IV Castration Sensitive Prostate Cancer Condition: Prostate Cancer, Stage IV Prostate Cancer, Advanced Prostate Cancer, Adenocarcinoma of the Prostate Intervention: Drug: Adaptive Androgen Deprivation Therapy (ADT) Drug: Abiraterone Drug: Prednisone Purpose: Adaptive Androgen Deprivation Therapy (ADT) plus Standard […]

A Multicentre Cohort Study of Patients With Advanced Prostate Cancer in Canada Condition: Prostatic Neoplasms Intervention: Other: Standard of Care Purpose: The purpose of this study is to document the course of advanced prostate cancer in Canada in terms of disease progression, real-world treatment, and patient management. Study Type: Observational Clinical Trials Identifier NCT 8-digits: […]

A Phase 2 Trial Using Gilotrif for Advanced Penile Squamous Cell Carcinoma Following Systemic Therapy Condition: Penile Squamous Cell Carcinoma (PSCC) Intervention: Drug: Gilotrif Purpose: Penile squamous cell carcinoma (PSCC) is a highly aggressive and relatively rare disease. Supportive evidence for the value of systemic therapy does not exist for this disease and there are […]

Ralph Clayman: I’m going to share with you just a few thoughts and some experiences that I have. Quite frankly, I believe I’m the warmup act for Dr. Belldegrun who’s really done this to the Nth degree. I am a piker in his presence. So I’m going to cover five areas, seminal whys, creativity, innovation, […]

Increasing evidence suggests that cancer progression is strongly influenced by the host immune response, which is represented by immune cell infiltrates. The T-lymphocyte-based Immunoscore is reported to be a reliable prognostic factor in colon cancer, but its significance in urothelial carcinoma of the bladder (UCB) is at an early stage of exploration. This study aimed […]

To evaluate the efficacy of Bacilli Calmette-Guerin (BCG) induction instillation therapy after second transurethral resection (TUR) in stage Ta T1 high-grade bladder cancer. We performed a retrospective analysis of 49 consecutive new onset Ta T1 high-grade bladder cancer patients treated with second TUR at our affiliated institutions. Residual cancer rate, intravesical recurrence-free survival (RFS), and […]