To illustrate a technique of robotic vesicovaginal fistula repair in a patient with a prior history of pelvic radiation therapy and multiple abdominal surgeries. Stepwise demonstration of the technique with narrated video footage.
Cytoreductive radical prostatectomy (CRP) may offer a survival advantage, according to several retrospective analyses. However, no direct comparisons are available regarding the type of surgical approach (open vs.
To describe a new technique for robot-assisted AMS-800 artificial urinary sphincter bladder neck implantation in female patients. We reviewed the medical files of patients who underwent robot-assisted artificial urinary sphincter (R-AUS) implantation from March 2017 to November 2018 at our centre.
The Philippine Endourological Society hosted a soft cadaveric workshop last August 2-3, 2019 at the Philippine Center for Advanced Surgery at the Cardinal Santos Medical Center. This was made possible through the invaluable support of Medtronic and PCAS.
A PHASE I DOSE ESCALATION AND EXPANDED COHORT STUDY OF PF-06821497 IN THE TREATMENT OF ADULT PATIENTS WITH RELAPSED/REFRACTORY SMALL CELL LUNG CANCER (SCLC), CASTRATION RESISTANT PROSTATE CANCER (CRPC) AND FOLLICULAR LYMPHOMA (FL) Condition: Small Cell Lung Cancer (SCLC), Follicular Lymphoma (FL), Castration Resistant Prostate Cancer (CRPC), Diffuse Large B-Cell Lymphoma (DLBCL) Intervention: Drug: PF-06821497 […]
A Phase 1b/2 Study of CPI-1205, a Small Molecule Inhibitor of EZH2, Combined With Enzalutamide or Abiraterone/Prednisone in Patients With Metastatic Castration Resistant Prostate Cancer Condition: Metastatic Castration Resistant Prostate Cancer (mCRPC) Intervention: Drug: CPI-1205 Drug: Enzalutamide Drug: Abiraterone/Prednisone Purpose: This is a two-arm, open label Phase 1b/2 study with an oral administration of CPI-1205 […]
In penile cancer, lymph node (LN) metastasis is the main known prognostic factor that affects survival. Inguinal sentinel LN (SLN) dissection (sLND) using radioactive marking is recommended by the European Association of Urology guidelines to evaluate the nodal status in clinically node-negative penile cancer (cN0; ≥pT1, G2). Dependence on radioisotopes limits the application of this […]
Limited data compare first-line carboplatin-based chemotherapy and immune checkpoint blockade in cisplatin-ineligible metastatic urothelial carcinoma (mUC) patients. The primary evidence guiding treatment decisions was a recent Food and Drug Administration/European Medicines Agency safety alert based on emerging data from two ongoing phase III trials, reporting shorter survival in programmed death-ligand 1 (PD-L1)-negative patients receiving immunotherapy. […]
The sarcomatoid morphology of muscle-invasive bladder cancer (MIBC) is associated with unfavorable prognosis. However, the genomic, transcriptomic, and proteomic relationship between conventional urothelial and synchronous sarcomatoid morphology is poorly defined. We compiled a cohort of 21 MIBC patients with components of conventional urothelial and adjacent sarcomatoid morphology within the same tumor focus. We performed comprehensive […]
The effect of local treatment on survival in advanced-stage patients has gained interest in several malignancies; however, limited data exist regarding urothelial carcinoma (UC). To test the impact of surgery of the primary tumor site on cancer-specific mortality (CSM) and overall mortality (OM) in patients affected by metastatic UC. Individual patient-level data from a multicenter […]
