A 71-yr-old man was transferred to our institution with multiple and recurrent high-grade pTa bladder cancer 26mo after an initial presentation of multiple and large pTa low-grade tumors and concomitant carcinoma in situ, treated with transurethral resection plus 6-mo postoperative mitomycin C. This case discusses several treatment options in the absence of bacillus Calmette-Guérin (BCG). […]
A 72-year old male presented with muscle invasive bladder cancer was counseled on the standard of care neoadjuvant chemotherapy and he started treatment. He then presented with anemia, blood in the stool and gas in the right renal pelvis and was diagnosed with Pyeloduodenal fistula. The fistula was treated with clipping by gastroenterology and the […]
Bladder cancer is a heterogeneous group of tumours with at least 40 histological subgroups. Patients with localized disease can be cured with surgical resection or radiotherapy, but such curative options are limited in the setting of recurrent disease or distant spread, in which case systemic therapy is used to control disease and palliate symptoms. Cytotoxic […]
Most patients with prostate cancer are diagnosed with low-grade, localized disease and may not require definitive treatment. In 2012, the U.S. Preventive Services Task Force (USPSTF) recommended against prostate cancer screening to address overdetection and overtreatment. This study sought to determine the effect of guideline changes on prostate-specific antigen (PSA) screening and initial diagnostic stage […]
The purpose of this research was to carry out a statistical study (the first such) of prostate-specific antigen (PSA) levels in Puerto Rican men (including residents of Puerto Rico not born on the island) with proven prostate cancer (PC). We also sought to propose new age-specific PSA reference ranges to improve the diagnosis and prognosis […]
Prostate cancer (PCa) is the most common cancer in men worldwide, but it exhibits a highly variable biological behavior ranging from indolent to highly aggressive disease. The standard conventional imaging for staging PCa consists of CT, MRI, and bone scans, but this imaging has suboptimal accuracy for extraprostatic tumor detection, particularly in the scenario of […]
This review aimed to systematically evaluate the characteristics of technology-based interventions (TBIs) and their effectiveness on anxiety, depression, and health-related quality of life (HRQoL) among patients with prostate cancer. We identified eligible research reports published in English language between January 1, 2000, and September 15, 2018, from CINAHL; Embase; “Library and Information Science Abstracts”; “Library, […]
The early detection of prostate cancer can significantly optimize the prognosis, prolong patient lifespan, and improve quality of life. It has been well documented that prostate cancer tissues have lower zinc content than normal prostate tissues due to an impairment of the zinc accumulation mechanism. A novel diketopyrrolopyrrole (DPP)-based fluorescent zinc ion probe named DPP-C2 […]
Abdominal imaging leads to the detection of a large number of renal tumors without the ability to distinguish the type of tumor detected. It is necessary to find a precise way to know the type of tumor to determine the appropriate treatment. The use of urine samples for detecting new biomarkers especially proteins has a […]
The primary objective of this study was to evaluate outcomes and prognosticators in patients who underwent radical nephrectomy (RN) or cytoreductive nephrectomy (CN), depending on the clinical stage of disease preoperatively, with a pathological T4 (pT4) renal cell carcinoma (RCC) outcome. There is little data on the outcome of this specific subset of patients. From […]
