Clear cell renal cell carcinoma (ccRCC) is one of the most common types of kidney cancer and is accompanied by a poor prognosis due to a high potential for metastasis and recurrence. The mechanism of ccRCC metastasis is not well known. N-lysine methyltransferase KMT5A serves a crucial role in the progression of human cancer; however, […]
Many patients with small renal masses (SRM) undergo surgical resection of benign and potentially indolent renal masses. We review the available literature to quantify the proportion of renal tumors that are low-risk based on clinical radiographic size, and quantify the number of low-risk masses surgically removed in the United States. We systematically reviewed the literature […]
This is an extraordinary time in urology. After decades of relative stagnation, patients with urothelial carcinoma are receiving approved immuno-oncologic drugs that significantly extend survival and are safer and more tolerable than chemotherapy. The success of these treatments in metastatic bladder cancer has generated strong interest and promising early results for their use in localized […]
The debate on the pros and cons of robot-assisted partial nephrectomy performed with (on-clamp) or without (off-clamp) renal artery clamping is ongoing. The aim of this meta-analysis is to summarize the available evidence on the comparative studies assessing the outcomes of these two approaches.
To report and compare the peri-operative outcomes of patients undergoing open (ORC) and robotic-assisted radical cystectomy (RARC) for bladder cancer performed with a radiofrequency seal and cut device (Caiman®).
While urothelial carcinoma of the bladder is often considered a multifocal disease, the location of the dominant tumor may be prognostic. To determine the association between intravesical tumor location and both adverse pathological outcomes as well as overall survival. Patients in the National Cancer Database (2010-2015) with nonmetastatic urothelial carcinoma of the bladder who underwent […]
The objective of this study was to evaluate the diagnostic accuracy of the Bladder EpiCheck test in the follow-up of patients with non-muscle-invasive bladder cancer (NMIBC) and to compare it with the accuracy of urinary cytology, cystoscopy, and/or histology. In total, 243 patients were enrolled in the current study. Patients were evaluated by voided urine […]
The aim of the study was to investigate the feasibility of Epidermal Growth Factor Receptor (EGFR) measurement in bladder washings of patients affected by non-muscle-invasive bladder cancer (NMIBC) and its prognostic role in identifying risk subgroups and predicting disease recurrence and progression. Patients with NMIBC treated with transurethral resection of bladder tumor (TURBT) from 2012 […]
Prostate cancer ranks second among male cancers in the United States in terms of death rate. Robot-assisted surgery (RAS) is now offered as the standard surgical procedure performed for radical prostatectomy. Urinary incontinence and erectile dysfunction were common complications after RAS prostatectomy. Patients felt ill-prepared after surgery, resulting in negative impacts on their quality of […]
To analyze long-term quality of life (QoL) changes related to postoperative radiotherapy (RT) after radical prostatectomy. Patients following postoperative 3D conformal RT in the years 2003-2008 with 1. 8-2.0Gy fractions up to 66.0-66.6Gy (n=181) were surveyed using the EPIC (Expanded Prostate Cancer Index Composite) questionnaire before the beginning of RT (A), at the last day […]
