SIU 2021: What Trials Do We Need in Advanced Renal Cell Carcinoma to Improve Outcomes  

(UroToday.com) The Société Internationale D’Urologie (SIU) 2021 annual meeting included a master class on advanced kidney cancer with a presentation by Dr. Axel Bex discussing the trials we need in advanced renal cell carcinoma (RCC) to improve outcomes. Dr. Bex started his talk by highlighting the danger of radiological window dressing noting that there are two […]

Positive Preliminary Data from Phase 1b Trial Evaluating Batiraxcept (AVB-500) in Combination with Cabozantinib for Treatment of Clear Cell Renal Cell Carcinoma

7 of 16 (44%) patients achieved best overall response of partial response Confirmed response in 5 of 7 (71%) patients who had at least 16 weeks of follow-up 14 of 16 (88%) patients demonstrated tumor decrease from baseline Batiraxcept has been well-tolerated with no dose-limiting toxicities San Francisco, CA (UroToday.com) — Aravive, Inc., a clinical-stage oncology […]

First-line Nivolumab plus Ipilimumab Versus Sunitinib in Patients Without Nephrectomy and With an Evaluable Primary Renal Tumor in the CheckMate 214 Trial.

We present an exploratory post hoc analysis from the phase 3 CheckMate 214 trial of first-line nivolumab plus ipilimumab (NIVO+IPI) versus sunitinib in a subgroup of 108 patients with advanced renal cell carcinoma (aRCC) without prior nephrectomy and with an evaluable primary tumor, a population under-represented in clinical trials.

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