Treatment of metastatic urothelial carcinoma is currently undergoing a rapid evolution. This overview presents the updated European Association of Urology (EAU) guidelines for metastatic urothelial carcinoma.
Radical open nephroureterectomy (ONU) with bladder cuff excision (BCE) is the traditional gold standard approach for management of high-risk non-metastatic upper tract urothelial cancer. ONU involves two separate procedures; the nephrectomy and distal ureterectomy, with each of these parts being able to be performed with an open or minimally-invasive approach.
Salvage radiotherapy (SRT) is utilized for biochemical progression of prostate cancer after radical prostatectomy (RP). To report the outcomes of the SAKK 09/10 trial comparing conventional and dose-intensified SRT.
It is profound that despite years of intensive therapeutic efforts, 50-60% of patients with muscle-invasive urothelial bladder cancer will have a local or distant disease recurrence within 5 years with limited further therapy options. The primary research goal of our translational working group is to promote personalized therapy for patients with muscle-invasive bladder cancer patients […]
Human papillomavirus (HPV) is associated with up to 4.5% of all cancer cases and is a significant healthcare burden, with 600 000 cases per annum. HPV vaccination has been introduced globally to mitigate this public health risk. Prophylactic vaccines against high-risk (HPV-16 and HPV-18) and low-risk (HPV-6 and HPV-11) HPV subtypes have revolutionised the field. […]
Linda Budzinski: Can you comment on your experience with PYLARIFY DCF PyL and how it impacts your management of men at staging? Does it potentially change your surgical approach? Second, do you think these PSMA scans will replace conventional imaging and staging? And third, in the BCR setting, what is your threshold for PSMA scanning […]
Steven Rowe: A few other things, that may be salient to an audience, primarily composed of urologists. I’m going to focus a little bit more on metastatic disease, both small volume oligometastatic disease, as well as more widespread metastatic disease, and the role of PSMA PET in those contexts. I’m going to talk a little […]
During the coronavirus disease 2019 pandemic, US unemployment rates rose to historic highs, and they remain nearly double those of prepandemic levels. Employers are the most common source of health insurance among nonelderly adults.
The androgen receptor (AR) pathway is a key driver of neoplastic behaviour in the different stages of metastatic prostate cancer (mPCa). Targeting the AR therefore remains the cornerstone for mPCa treatment.
Worldwide, we have witnessed an expansion of robot-assisted laparoscopic surgery (RALS) and thanks to the global adoption of high-resolution diagnostic imaging technologies, an increased incidence of newly diagnosed prostatic, renal and bladder cancers has been recorded with concurrent second primary urological cancer diagnoses increasing by 1.
