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The relationship between preoperative physical activity (PA) and hospital length of stay (LOS) following radical prostatectomy (RP) is poorly understood. In addition, the relationship between PA and the American Society of Anesthesiologists Physical Status score (ASA PS), an established prognosticator of surgical risk, has not been studied.

The BULLSEYE trial is a multicenter, open-label, randomized controlled trial to test the hypothesis if 177Lu-PSMA is an effective treatment in oligometastatic hormone-sensitive prostate cancer (oHSPC) to prolong the progression-free survival (PFS) and postpone the need for androgen deprivation therapy (ADT).

The purpose of this review is to look at recent advancements and treatment options of systemic therapies to treat penile squamous cell carcinoma (PSCC). PSCC is a rare cancer that remains with limited funding for research and systemic therapy development.

Many studies identified that the preoperative neutrophil-to-lymphocyte ratio (PNLR) was associated with patient prognosis in non-muscle-invasive bladder cancer (NMIBC). We hypothesized that PNLR could be prognostic in patients with histological variants of NMIBC (VH-NMIBC).

The treatment landscape for advanced urothelial cancer has changed dramatically owing to the US Food and Drug Administration approval and introduction of antibody-drug conjugates (ADCs), including enfortumab vedotin and sacituzumab govitecan.

The urinary tract likely plays a role in the development of various urinary diseases due to the recently recognized notion that urine is not sterile. In this mini review, we summarize the current literature regarding the urinary microbiome and mycobiome and its relationship to various urinary diseases.

(UroToday.com) The International Kidney Cancer Symposium 2021 annual hybrid meeting included a Keynote Address by 2018 Nobel Prize laureate Dr. James Allison who discussed immune checkpoint blockade in cancer therapy. Dr. Allison started his talk by noting that in 1996, based on data regarding signals that regulate T cell responses, Dr. Allison hypothesized that tumor cells, […]

(UroToday.com) The International Kidney Cancer Symposium 2021 annual hybrid meeting included a non-clear cell renal cell carcinoma (RCC) session and a presentation by Dr. Kun-Liang Guan discussing the role of NF2 in tumorigenesis and specifically the Hippo pathway and cancer. Dr. Guan started by highlighting that the Hippo pathway plays a key role in organ size […]

(UroToday.com) The International Kidney Cancer Symposium 2021 annual hybrid meeting included a role of perioperative therapy in renal cell carcinoma (RCC) session and a presentation by Dr. Mohamad Allaf discussing surgical considerations with perioperative therapy. Dr. Allaf notes that TKIs have been used as monotherapy or in combination with immunotherapy in the neoadjuvant setting, adjuvant setting, […]

(UroToday.com) The International Kidney Cancer Symposium 2021 annual hybrid meeting included a role of perioperative therapy in renal cell carcinoma (RCC) session and a presentation by Dr. Christopher Weight discussing the use of artificial intelligence for RCC diagnosis of CT scans. Dr. Weight notes that there has been substantial hype around artificial intelligence, and in 2016 […]