Comparison of clinicopathologic and oncological outcomes between Trans-Urethral En Bloc (TUEB) Resection and Conventional Trans-Urethral Resection of Bladder Tumor (cTURBT): a systematic review, meta-analysis and network meta-analysis with focus on Differ

It has been hypothesized that transurethral en bloc resection of bladder tumor (TUEB) offers benefits over conventional transurethral resection of bladder tumor (cTURBT). This study aimed to compare disease outcomes of TUEB and cTURBT with focus on the different energy sources.

TRANSCRIPT: VIDEO ID 2375 Cisplatin-Related Immunomodulation and Efficacy with Atezolizumab + Cisplatin Versus Carboplatin-Based Chemotherapy in Metastatic Urothelial Cancer – Matthew Galsky

Alicia Morgans: Hi, my name is Alicia Morgans, and I’m a GU medical oncologist at Dana Farber Cancer Institute in Boston. I’m so excited to talk today with a good friend and colleague, Dr. Matt Galsky, who’s a professor of medicine and the director of GU Medical Oncology at Mount Sinai in New York. Thank […]

Efficacy of Adding Panitumumab to Dose-Dense MVAC Chemotherapy in Patients with Advanced Urothelial Cancer – Expert Commentary

Platinum-based chemotherapy is the cornerstone of initial treatment for most patients with advanced urothelial cancer (UC). EGFR is a promising target given its high expression levels in UC and the availability of anti-EGFRs inhibitors. However, it is unclear if adding an anti-EGFR inhibitor to platinum-based chemotherapy will lead to better clinical outcomes.

Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin With or Without Panitumumab in Patients With Advanced Urothelial Carcinoma: Multicenter, Randomized, French Unicancer GETUG/AFU 19 Study

This study looked at whether epidermal growth factor receptor inhibition by the monoclonal antibody panitumumab could increase the efficacy of standard chemotherapy in advanced urothelial cancer. Results were disappointing, with higher toxicity and no improvement in efficacy in the combination arm.

Nerve-sparing Robot-assisted Retroperitoneal Lymph Node Dissection: The Monoblock Technique.

Retroperitoneal lymph node dissection (RPLND) is a treatment option for men with stage 1 or 2 testis cancer and the standard of care for men with postchemotherapy retroperitoneal residual disease. Given the morbidity of RPLND, four important surgical modifications have been proposed: minimally invasive access, nerve-sparing resection, template resection, and en-bloc resection.

Real-World Incidence of Immune-Related Adverse Events Associated with Nivolumab Plus Ipilimumab in Patients with Advanced Renal Cell Carcinoma: A Retrospective Observational Study.

Real-world incidence of immune-related adverse events (irAEs) associated with nivolumab plus ipilimumab in patients with renal cell carcinoma (RCC) has been rarely demonstrated. The present study aims to report the safety outcomes of this combination therapy in the real-life population.

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