The heterogeneity of prostate cancer is evident at clinical, morphological and molecular levels. To aid clinical decision making, a three-tiered system for risk stratification is used to designate low-, intermediate-, and high-risk of disease progression.
There is considerable evidence of a positive association between the incidence of type 2 diabetes mellitus (T2DM) and obesity with bladder cancer (BCa), with the link between T2DM and obesity having already been established.
For decades, limited options existed to treat metastatic genitourinary cancers, including treatment options that could be classified as immunotherapy. Historically, immunotherapy centered on systemic cytokines for the treatment of metastatic kidney cancer, which had several adverse effects, as well as the Bacillus Calmette-Guérin vaccine for non-metastatic bladder cancer.
Patients with brain metastases from renal cell carcinoma (RCC) have been underrepresented in clinical trials, and effective systemic therapy is lacking. Cabozantinib shows robust clinical activity in metastatic RCC, but its effect on brain metastases remains unclear.
We address novelty regarding metabolomic profiling in renal cell carcinoma (RCC) patients, in an attempt to postulate potential treatment strategies. A large-scale literature search in existing scientific websites focusing on the keywords "renal cell carcinoma", "clear cell histology", "papillary histology", "metabolomic profiling", and "therapeutics" was performed.
Bolstering the next frontrunners and stimulating research in urology are the core objectives of the European Urological Scholarship Programme (EUSP). Through year-long scholarships, clinical visits, and fellowships, the EUSP encourages knowledge exchange and provides valuable experience to young, promising participants. These commendable goals parallel the enthusiasm and drive of renowned expert, Prof. Axel Merseburger (DE), […]
Alicia Morgans: Hi, my name is Alicia Morgans, and I’m a GU Medical Oncologist, at Dana-Farber Cancer Institute, in Boston. I’m so excited to have here with me today, a friend and colleague Dr. Wassim Abida, who’s a GU medical oncologist, at Memorial Sloan Kettering Cancer Center, in New York. Thank you so much for […]
Urinary incontinence (UI) in women is a dynamic condition with numerous risk factors yet most studies have focused on examining its prevalence at a single time. The objective of this study was to describe the long-term time course of UI in women with type 1 diabetes (T1D).
Observational studies among older women have associated vitamin D insufficiency with greater prevalence and incidence of urinary incontinence than older women with adequate vitamin D status. Less is known about the effect of vitamin D supplementation on reducing incontinence.
To assess the safety and effectiveness of mirabegron in patients with PD complaining of overactive bladder (OAB). From January 2017 to November 2020, we performed a prospective randomized, double-blind, placebo-controlled trial that enrolled PD patients with symptoms of OAB.
