Metastasectomy in kidney cancer: current indications and treatment approaches.

Although systemic agents for the treatment of metastatic renal cell carcinoma (mRCC) have improved survival, remission and cure for mRCC remains rare with systemic therapy alone. However, there is a body of observational evidence supporting a survival benefit in mRCC among patients who undergo complete surgical consolidation including resection of the primary tumor and all […]

The Journal of Urology Publishes Results of the Phase 2b Study of UGN-102 in Patients with Low-Grade Intermediate Risk Non-Muscle Invasive Bladder Cancer

Clinically Meaningful Response and Sustained Durability Underscore Potential for UGN-102 to Become a Non-Surgical Primary Therapeutic Treatment for Patients with Highly Recurrent LG IR-NMIBC 65% Complete Response (CR) Rate at Three Months 61% of Patients Remain in CR at 12 Months Data Supports Ongoing Phase 3 Development of UGN-102 in LG IR-NMIBC as an Alternative […]

TRANSCRIPT: VIDEO ID 2341: NCCN Clinical Practice Guidelines nuances in advanced prostate cancer – neuroendocrine disease, bone and visceral metastases, and treatment sequencing

Christopher Wallis: Hello, and thank you for joining us for a UroToday discussion, of NCCN Clinical Practice Guidelines in Oncology. Today we’re focusing on the prostate cancer guidelines of February 2021, with a focus on nuances in advanced prostate cancer, including neuroendocrine disease, bone and visceral metastases, and treatment sequencing. I’m Chris Wallis, an Assistant […]

TRANSCRIPT: VIDEO ID 2340: JC NCCN Guidelines PCa epidemiology Initial Diagnosis Life Expectancy

Zachary Klaassen: Hello, and thank you for joining us for this NCCN Clinical Practice Guideline in Oncology Prostate Cancer discussion. Today, we’ll be discussing the epidemiology, initial diagnosis, and life expectancy with prostate cancer. My name is Zachary Klaassen. I’m an Assistant Professor at the Division of Urology at the Medical College of Georgia. And […]

EAU and partners submit joint letter to ask for continued support from MEPs on prostate cancer

The amendments to the “Strengthening Europe in the fight against cancer – towards a comprehensive and coordinated strategy” report from the European Parliament Special Committee on Beating Cancer (BECA Committee) have come in. We are delighted to see that our collective advocacy with European cancer patients and researchers has led to strong messages on prostate cancer. Over […]

Nivolumab in Combination with Stereotactic Body Radiotherapy in Pretreated Patients with Metastatic Renal Cell Carcinoma. Results of the Phase II NIVES Study.

Nivolumab showed an overall survival (OS) benefit in pretreated metastatic renal cell carcinoma (mRCC). The role of stereotactic body radiotherapy (SBRT) in mRCC remains to be defined. Our aim was to evaluate the efficacy and safety of SBRT in combination with nivolumab in second- and third-line mRCC patients.

Treatment-free survival after discontinuation of immune checkpoint inhibitors in metastatic renal cell carcinoma: a systematic review and meta-analysis.

While immune checkpoint inhibitors (ICI) can lead to sustained responses in metastatic renal cell carcinoma (mRCC), the optimal duration of therapy remains unknown. We aimed to examine treatment-free survival (TFS) in objective responders who discontinued ICI and to explore factors that may impact objective response rate (ORR) and TFS.

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