Current guidelines do not provide strong recommendations on the preservation of the neurovascular bundles during RP in case of HR PCa and/or suspicious EPE. We aimed to evaluate when, in case of unilateral HR disease, contralateral NS should be considered or not.
We are now in an era of molecular medicine, where specific DNA alterations can be used to identify patients who will respond to specific drugs. However, there are only a handful of clinically used predictive biomarkers in oncology.
Multiparametric MRI localizes cancer in the prostate, allowing for MRI guided biopsy (MRI-GB) 43 alongside transrectal ultrasound-guided systematic biopsy (TRUS-GB). Three MRI-GB approaches exist; visual estimation (COG-TB); fusion software-assisted (FUS-TB) and MRI ‘in-bore’ biopsy (IB-TB).
The aim of this study was to assess acute and late morbidity measured by the physician and patient-reported outcomes (PROs) in high-risk prostate cancer (PC) patients receiving whole pelvic intensity-modulated radiotherapy (IMRT) in the setting of a national clinical trial.
The use of sequential intravesical instillation of gemcitabine and docetaxel in the management of bacillus Calmette-Guérin-unresponsive non-muscle-invasive bladder cancer should not be recommended as a second-line treatment.
Prior research has shown that concordance with the guideline-endorsed recommendation to re-resect patients diagnosed with primary T1 bladder cancer (BC) is suboptimal. Therefore, the aim of this population-based study was to identify factors associated with re-resection in T1 BC.
The incidence and risk factors for metachronous upper tract urothelial carcinoma (UTUC) following radical cystectomy (RC) remain incompletely defined, which has limited the ability to individualize postoperative surveillance.
The European School of Urology (ESU) offers you 16 free e-courses dedicated to the EAU Guidelines. Every year, when the new edition of the EAU Guidelines is released, renowned experts meticulously select vital points in the new Guidelines and integrate them in the ESU e-courses. This guarantees that you update your knowledge with the latest […]
(UroToday.com) In this presentation, Dr. Mozzi Etemadi discussed how computer programs, often referred to as artificial intelligence, can be used for cancer-based applications such as cancer screening.
Deletions of PTEN are common in metastatic CRPC, particularly as early driver events, and lead to constitutive activation of PI3K/AKT/mTOR signaling pathways. Such activation not only readily feeds forward to drive cellular proliferation and survival, but, in prostate cancer specifically, can permit evasion of AR-targeted therapies. Consequently, the authors completed a phase I study to […]
