Getting the Word Out

Consider this the first of a series of messages on the mission and strategy of the Prostate Cancer Foundation (PCF). The mission of PCF is to reduce the death and suffering from prostate cancer. I often wonder about what would be a good analogy for the mission. As one travels through the world of medical […]

Can PARP Inhibitors Make It into the Metastatic Castration-Sensitive Prostate Cancer Disease State?

I’m continuing this series focused on metastatic castration-sensitive prostate cancer (mCSPC), as it is a disease state with many upcoming potential changes to standard of care.  A couple of months ago, I briefly summarized what is known about the PEACE-1 trial, and I highlighted ongoing chemohormonal therapy trials.1  Since then, there has been a press […]

Real-World Evidence of Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Cabazitaxel: Comparison with the Randomized Clinical Study CARD – Beyond the Abstract

The CARD study results were reported at the 2019 ESMO meeting and simultaneously published in the NEJM. CARD investigated the efficacy and safety of cabazitaxel as compared with an androgen-receptor-signaling inhibitor ( ARSI; abiraterone or enzalutamide), in patients with mCRPC who were previously treated with docetaxel and had progressed within 12 months while receiving the […]

Survival Outcomes in Men with Unfavorable Intermediate-Risk and High-Risk Prostate Cancer Treated with Prostate-only versus Whole Pelvic Radiation Therapy.

Men with unfavorable intermediate-risk (UIR-PCa) or high-risk prostate cancer (HR-PCa) are often treated with definitive external beam radiotherapy (EBRT) plus androgen deprivation therapy (ADT). Treatment is frequently intensified by electively treating the pelvic lymph nodes (LN) with whole pelvis radiotherapy (WPRT), but practice patterns and the benefits of WPRT are not well defined.

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