ESMO 2021: Results of the GETUG/AFU VESPER V05 Phase III Trial (ddMVAC vs GC in MIBC) and the Phase II Trial of Pembrolizumab plus sEphB4-HSA in Metastatic Urothelial Carcinoma

(UroToday.com) In this presentation, Dr. Enrique Grande discussed the results of the GETUG/AFU VESPER V05 Phase III Trial and the Phase II trial of pembrolizumab plus sEphB4-HSA in metastatic urothelial carcinoma (UC). These two studies led to exciting results with the potential to impact practice for patients with urothelial carcinoma in the future.

ESMO 2021: Erdafitinib or Erdafitinib Plus Cetrelimab for Patients with Metastatic or Locally Advanced Urothelial Carcinoma and Fibroblast Growth Factor Receptor Alterations: First Phase 2 Results From the NORSE Study

(UroToday.com) The European Society of Medical Oncology (ESMO) 2021 annual meeting’s non-prostate cancer preferred paper session included a presentation by Dr. Thomas Powles discussing the first phase 2 results from the NORSE study assessing erdafitinib or erdafitinib plus cetrelimab for patients with metastatic or locally advanced urothelial carcinoma and fibroblast growth factor receptor (FGFR) alterations. First-line […]

ESMO 2021: The Phase 2 NORSE Trial Discussion: Erdafitinib or Erdafitinib Plus Cetrelimab for Patients With Metastatic or Locally Advanced Urothelial Carcinoma and FGFR Alterations

(UroToday.com) The European Society of Medical Oncology (ESMO) 2021 meeting’s proffered paper session for non-prostate genitourinary tumors included a discussant presentation by Dr. Srikala Sridhar of the phase 2 NORSE trial assessing erdafitinib or erdafitinib plus cetrelimab for patients with metastatic or locally advanced urothelial carcinoma and fibroblast growth factor receptor (FGFR) alterations. Dr. Sridhar started […]

ESMO 2021: Analysis of Serial PET Imaging and Paired Tc99 Scans in Metastatic Castration Resistant Prostate Cancer (mCRPC) Treated with Enzalutamide,

(UroToday.com) In the on-demand poster session of the European Society for Medical Oncology (ESMO) Annual Congress, Dr. Madan provided an assessment of a semi-automated method of assessing Sodium Fluoride (NaF) PET using a novel technology. This is particularly relevant given that current and emerging PET platforms are enhancing clinicians’ ability to evaluate metastatic lesions in mCRPC.

ESMO 2021: Dose-Dense Methotrexate, Vinblastine, Doxorubicin and Cisplatin or Gemcitabine and Cisplatin as Perioperative Chemotherapy for Patients with MIBC: GETUG/AFU VESPER V05 Phase III Trial

(UroToday.com) In this presentation, Dr. Christian Pfister presented results of the GETUG/AFU VESPER V05 phase III clinical trial, which compared dose-dense Methotrexate, Vinblastine, Doxorubicin and Cisplatin (ddMVAC) versus Gemcitabine and Cisplatin (GC) as perioperative chemotherapy for patients with muscle-invasive bladder cancer (MIBC). The standard of care for MIBC in 2021 is radical cystectomy with perioperative chemotherapy, […]

ESMO 2021: Health-Related Quality of Life (HRQoL) in ACIS: a Phase 3 Trial of Apalutamide With Abiraterone Acetate and Prednisone (APA + AAP) vs AAP in Metastatic Castration-Resistant Prostate Cancer (mCRPC),

(UroToday.com) In the on-demand poster session of the European Society for Medical Oncology (ESMO) Annual Congress, Dr. Stephane Oudard presented data on patient-reported health-related quality of life (HRQoL) in the context of the ACIS trial (NCT02257736). This phase III trial randomized patients with metastatic castration resistant prostate cancer (mCRPC) to receive either abiraterone acetate and prednisone […]

ESMO 2021: The Role of Radiotherapy

(UroToday.com) As a portion of the European Society for Medical Oncology (ESMO) Annual Congress, an Educational Session focused on the management of patients with node-positive locally advanced prostate cancer was held. In this context, Dr. Chris Parker discussed the role of radiotherapy for these patients. He began by emphasizing that there are no randomized controlled trials […]

ESMO 2021: Pain Efficacy With Radium-223 in Patients With Metastatic Castration-Resistant Prostate Cancer in the PARABO Observational Study

(UroToday.com) In the on-demand poster session of the European Society for Medical Oncology (ESMO) Annual Congress, Dr. Holger Palmedo reported results of the PARABO cohort (NCT02398526), a prospective, observational, noninterventional, single-arm study evaluating pain efficacy in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with Radium-223 in German real-life nuclear medicine settings.

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