IC/BPS is a chronic progressive disorder that is often difficult and unsatisfactory for the person affected and the treating therapist. Treatment should therefore be comprehensive, interdisciplinary, multimodal and take into account the biopsychosocial model.
Potential complications after inguinal hernia repair include uncontrolled post-operative pain and post-operative urinary retention (POUR). Enhanced Recovery After Surgery (ERAS) protocols aim to mitigate post-operative morbidity.
An oral capsule combining finasteride and tadalafil was recently approved in the USA for signs and symptoms of benign prostatic hyperplasia (BPH). The authors argue that this new formulation has a limited role in the management of BPH and represents an avoidable prescribing cascade and low-value care.
Incorporating neoadjuvant chemotherapy (NAC) into the management of patients with localized muscle-invasive bladder cancer (MIBC) improves survival. However, due to multiple factors, NAC is still not effectively used in real-life settings. Moreover, there is are established predictor biomarkers to guide clinicians to choose the most beneficial treatment with the least possible toxicities.
We regret to inform you that we have been forced to postpone the 37th Annual EAU Congress in Amsterdam to late spring or early summer. The reason for this unfortunate decision is that the Dutch government’s rules and regulations currently do not permit the organisation of a meeting of our size. Although the Netherlands is […]
Surgery and stereotactic ablative body radiotherapy (SABR) are commonly utilised in the setting of oligometastatic renal cell carcinoma (RCC) with the potential for durable remission in select patients. A majority will, however, progress at other sites and ultimately require systemic therapy. Single-agent immune checkpoint inhibitor (ICI) therapy had shown promising activity in the second line […]
To review the pathway and pertinent materials leading to approval of PSMA scanning (prostate-specific membrane antigen) by the U.S. FDA. Beginning with the pivotal trials and working backward, we summarize the evolution of PSMA scanning, beginning with the discovery of the molecule, the mechanism of action to identify prostate cancer, the route to the present-day […]
To examine the context of relationship status on the link between friends/family social constraints (SCff) and cancer-related quality-of-life (QOL) among young adult testicular cancer survivors. Participants completed the Functional Assessment of Cancer Therapy (general version), the Social Constraints Scale (friends/family), and demographic questions.
There are various alternative first-line therapeutic options besides tyrosine kinase inhibitors (TKIs) for metastatic renal cell carcinoma (mRCC). To inform therapeutic decision-making for such patients, this study aimed to identify predictive factors for resistance to TKI.
The molecular heterogeneity of clear cell renal cell carcinoma (ccRCC) leads to a high mortality of the disease, which seriously threatens the life of patients. Therefore, this study explored the functional significance and mechanism of microRNA-155-5p and nuclear receptor subfamily 3 group C member 2 (NR3C2) in the regulation of ccRCC.
