Maintenance versus discontinuation of androgen deprivation therapy during continuous or intermittent docetaxel administration in castration-resistant prostate cancer patients: A multicentre, randomised Phase III study by the Piemonte Oncology Network.

This study was designed to demonstrate the non-inferiority (NI) in overall survival (OS) of suspension of androgen deprivation therapy (ADT) versus maintenance and intermittent versus continuous docetaxel administration in metastatic castration-resistant prostate cancer (mCRPC) patients.

Outcomes based on plasma biomarkers in METEOR, a randomized phase 3 trial of cabozantinib vs everolimus in advanced renal cell carcinoma.

In the phase 3 METEOR trial, cabozantinib improved progression-free survival (PFS) and overall survival (OS) versus everolimus in patients with advanced RCC after prior antiangiogenic therapy. In this exploratory analysis, plasma biomarkers from baseline and week 4 from 621 of 658 randomized patients were analyzed for CA9, HGF, MET, GAS6, AXL, VEGF, VEGFR2, and IL-8.

Urinary Catheter Alleviation Navigator Protocol (UCANP): Overview of Protocol and Review of Initial Experience – Beyond the Abstract

Given the associated morbidity and mortality with catheter associated urinary tract infections (CAUTIs), efforts should be made to mitigate the use of indwelling catheters. We sought to describe and report the results of the post-catheter removal bladder management protocol with particular focus on decreasing catheter reinsertion, catheter days, and CAUTIs. Urinary Catheter Alleviation Navigator Protocol […]

X