Penile cancer surgery affects physical, psychological, and sexual well-being, but the patient- and treatment-related factors predisposing to worse health-related quality of life (HRQoL) have not been well characterized.
Several immune checkpoint inhibitors (ICI) are approved for the treatment of advanced urothelial carcinoma (UC). There are limited biomarkers for ICI-treated UC patients. We investigated the association between body composition and clinical outcomes in ICI-treated UC patients.
The presence of carcinoma in situ at transurethral resection is known to increase the risk of recurrence and progression to invasive disease. However, the evidence regarding the prognostic role of concomitant carcinoma in situ after radical cystectomy due to bladder cancer is controversial.
To investigate the impact of rectal spacing on inter-fractional rectal and bladder dose and the need for adaptive planning in prostate cancer patients undergoing SBRT with a 0.35 T MRI-Linac. We evaluated and compared SBRT plans from prostate cancer patients with and without rectal spacer who underwent treatment on a 0.
In prostate cancer imaging, multi-parametric (mp) MRI is considered a valuable tool for local disease management and improvement in diagnosis. Recently, the National Institute of Health and Care Excellence (NICE) updated prostate cancer guidelines recommended the adoption of prostate mpMRI in all men with suspected prostate cancer prior to biopsy.
Previous studies highlighted the characteristics of the metastatic focus of prostate cancer (PCa) in pelvic lymph nodes (LN) as variables that could affect the outcome of radical prostatectomy. In addition, in recent years, the adoption of the surgical extended pelvic LN dissection has resulted in an increase in the rate of detection of LN metastasis. […]
To evaluate the value of image-based texture analysis for predicting progression-free survival (PFS) and overall survival (OS) in patients with metastatic clear cell renal carcinoma (cCCR) treated with nivolumab.
Renal cell carcinoma with sarcomatoid differentiation is a highly aggressive form of kidney cancer. We aimed to analyze the outcomes of patients treated with cabozantinib for metastatic renal cell carcinoma with sarcomatoid features.
Androgen deprivation therapy (ADT) for prostate cancer with luteinizing hormone-releasing hormone (LHRH) agonists can be improved. To assess safety, the frequency and severity of hot flushes (HFs), bone health, and antitumor effects of high-dose estetrol (HDE4) when combined with ADT.
Multiparametric magnetic resonance imaging (mpMRI) has improved risk stratification for suspected prostate cancer in patients following prior biopsy. However, not all significant cancers are detected by mpMRI.
