Bladder cancer is predominantly a disease of older adults. In the United States, 90% of diagnoses are made in patients over 55 y.o. and 80% in those over 65 y.o.1 According to the American Cancer Society Statistics, in 2021 an estimated 83,730 adults (64,280 men and 19,450 women) in the US will develop bladder cancer. […]
The purpose of our SEER analysis was to analyze potential differences in cancer-specific mortality (CSM) between races/ethnicities in metastatic prostate cancer treated with external beam radiotherapy to the prostate. Propensity score matching (3:1) accounted for patient age, prostate-specific antigen, clinical T and N stages, Gleason Grade Groups, and M1 substages between the largest reference group (Caucasians) […]
Although immunotherapy is now established as the newest pillar of cancer treatment, a basic question concerning how immune checkpoint inhibition works has yet to be addressed: “Where do the T cells that kill the tumor come from, and what do they look like?” In late 2017, we began to apply both CyTOF and single-cell sequencing […]
According to the American Urological Association and European Association of Urology guidelines, shockwave lithotripsy (SWL) is the least-invasive treatment option for kidney stones smaller than 2 cm.
Introduction The role of vitamin D in kidney stone disease is unclear. Current evidence and existing studies are inconsistent and inconclusive. The objective of this study is to assess the prevalence of vitamin D (VD) inadequacy (VDI) and metabolic abnormalities in urolithiasis patients presenting to a tertiary care center.
Nephrolithiasis has been increasing over the last millennium. Although early epidemiologic studies have shown that kidney stones were two to three times more frequent in males than in females, recent reports have suggested that this rate is decreasing.
The highest in quality data in the literature which compared mini percutaneous nephrolithotripsy (mPCNL), retrograde intrarenal surgery (RIRS) and shock wave lithotripsy (SWL) for the management of lower pole stone (LPS) with a maximal diameter ≤20mm were investigated by means of systematic review (SR) and meta-analysis.
Physical activity, a core intervention in cardiac rehabilitation, can reduce vascular erectile dysfunction (ED). ED is a common sensitive problem for men with cardiac diseases, decreasing their quality of life.
Patients with non-obstructive azoospermia (NOA) with a previous failed conventional TESE (cTESE) may undergo a salvage microdissection testicular sperm extraction (mTESE) with the probability of successful sperm retrieval (SSR) being almost dependent upon the number of previous surgical attempts and to different histopathologic categories OBJECTIVES: To determine whether the seminiferous tubules (STs) pattern and the […]
Penile traction therapy (PTT) aims to non-surgically reduce curvature, enhance girth, and recover lost length. Available clinical practice guidelines however lack clear recommendations regarding their use.
