The aim of this study is to describe the outcomes for a modified glans-resurfacing technique for benign and malignant penile conditions in which the uninvolved glans corona is preserved in order to maintain glans erogenous sensation.
As an alternative to radical cystectomy, tri-modality treatment (TMT) is an effective treatment approach for selected patients with muscle-invasive bladder cancer (MIBC). The purpose of this report is to contribute to the literature by summarizing institutional outcomes of a bladder-preserving TMT approach for patients with MIBC.
Muscle invasive bladder cancer (MIBC) is an aggressive disease with high rates of local recurrence following radical cystectomy (RC). Currently, there are no clinically validated biomarkers to predict local only recurrence (LOR) and guide adjuvant treatment decisions.
Irreversible electroporation (IRE) is a novel Food and Drug Administration-approved technology that utilizes high-voltage, short-pulse electrical currents to athermally ablate soft tissue. Multiple electrode probes are placed in an image-guided fashion into target tissues, and the application of energy across the probes results in cellular membrane pores and induces apoptosis. Within the field of urology, […]
Germline DNA damage repair (gDDR) alterations are common in men with prostate cancer (PCa). Men with PCa and gDDR alterations showed poor clinical outcomes. It is unclear if men with high-risk PCa and gDDR alterations would respond differently to neoadjuvant androgen deprivation therapy (ADT) than men without gDDR alterations.
According to the definition reported by the US National Cancer Institute, Active Surveillance (AS) is: “A treatment plan that involves closely watching a patient’s condition but not giving any treatment unless there are changes in test results that show the condition is getting worse. Active surveillance may be used to avoid or delay the need […]
While surgical margins can be minimal (3-5 mm) in penile cancer (PC) there is still a substantial group of patients with locally advanced or anatomically unfavorable PC in whom aggressive surgical intervention is necessary.1 In cases with bulky primary tumors total penectomy is indicated. In these patients, perineal urethrostomy is often the definitive form of urinary […]
Sam Chang: Hello, everyone. I’m Sam Chang, urologist at Vanderbilt University in Nashville, Tennessee. And I am happy to actually have an opportunity to share some knowledge with you today. That presentation actually given by Dr. Eugene Pietzak. Dr. Pietzak is an Assistant Professor and Assistant Attending Surgeon at Memorial Sloan Kettering Cancer Center. And he’s […]
– Collaboration combines Arvinas’ investigational estrogen receptor-targeting breast cancer therapy with Pfizer’s deep experience in breast oncology therapeutics –– ARV-471 is currently in Phase 2 development for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer –– Arvinas to receive $650 million in an upfront payment, in addition to a potential $1.4 […]
Decipher Biopsy is a commercially available gene expression classifier used in risk stratification of newly diagnosed prostate cancer (PCa). Currently, there are no prospective data evaluating its clinical utility.
