EAU 2021: Safety Evaluation of Sequential Mitomycin and BCG Treatment vs BCG Monotherapy in Patients With High Risk Non-Muscle Invasive Bladder Cancer: MITOBCG Study Preliminary

(UroToday.com) In this abstract, at the 2021 European Association of Urology (EAU) annual meeting, Dr. Cosimo De Nunzio et al. evaluate the safety of sequential Mitomycin-C (MMC) and Bacillus Calmette-Guérin (BCG) therapy compared to BCG monotherapy in patients with high risk non-muscle invasive bladder cancer (MIBC). The study is entitled MITOBCG and this abstract presentation highlights […]

EAU 2021: En-Bloc Versus Conventional Transurethral Resection of Bladder Tumors: Interim Analysis of a Single-Center Prospective Randomized Trial

(UroToday.com) At the non-muscle invasive bladder cancer (NMIBC) treatment and prognosis session at the European Association of Urology 2021 annual meeting Dr. Pietro Diana presented interim results of a single-center prospective randomized trial assessing en-bloc versus conventional transurethral resection of bladder tumors (TURBT). TURBT is considered the gold standard in the diagnosis and risk stratification of […]

EAU 2021: Diagnostic Accuracy of PSMA-PET-CT for Pelvic Lymph Node Staging in Men with Prostate Cancer Undergoing Radical Prostatectomy and Pelvic Lymph Node Dissection

(UroToday.com) Josias Grogg presented results of a study assessing the diagnostic accuracy of PSMA-PET-CT for pelvic lymph node staging in men with prostate cancer undergoing radical prostatectomy and pelvic lymph node dissection at the European Association of Urology 2021 annual meeting’s metastatic prostate cancer session. In men with newly diagnosed prostate cancer, only limited data describes […]

EAU 2021: The Effect of a Neoadjuvant Instillation of Chemotherapy in the Prevention of Recurrences of Non-Muscle Invasive Bladder Cancer: Preliminary Results of the PRECAVE Prospective, Controlled, Randomized Clinical Trial

(UroToday.com) At the non-muscle invasive bladder cancer (NMIBC) treatment and prognosis session at the European Association of Urology (EUA) 2021 annual meeting, Dr. Diego M. Carrion Monsalve discussed preliminary results of the PRECAVE randomized controlled trial assessing the effect of a neoadjuvant instillation of chemotherapy in the prevention of recurrences of NMBIC. Approximately half of patients […]

EAU 2021: Subgroup Analyses of the Phase 3 Study of Intravesical Nadofaragene Firadenovec in Patients with High-Grade, BCG-Unresponsive Non-Muscle Invasive Bladder Cancer

(UroToday.com) At the European Association of Urology 2021 annual meeting, Dr. Vikram M. Narayan, from Emory University presented results of several key subgroup analyses from the recently published trial assessing nadofaragene firadenovec in BCG-unresponsive NMIBC. The goals of treatment of NMIBC are to reduce recurrence and prevent progression, however, despite optimal treatment, ≥50% of patients who […]

EAU 2021: Significant Anti-Adenovirus Antibody Response Positively Correlates with Efficacy in Patients Treated with Nadofaragene Firadenovec for High-Grade BCG-Unresponsive Non-Muscle Invasive Bladder Cancer

(UroToday.com) At the 2021 European Association of Urology annual meeting, Vikram Narayan, discussed results of additional analysis assessing anti-adenovirus antibody response correlating with efficacy among patients in the phase III trial assessing nadofaragene firadenovec in patients with BCG unresponsive non-muscle invasive bladder cancer (NMIBC). This study was recently published in Lancet Oncology1. Nadofaragene firadenovec is a […]

New Concept Drug Hunts down Late Stage Prostate Cancer

San Francisco, CA (UroToday.com) — A new class of drug successfully targets treatment-resistant prostate cancers and prolongs the life of patients. The treatment delivers beta radiation directly to tumour cells, is well tolerated by patients and keeps them alive for longer than standard care, found a phase 3 trial to be presented at the European Association […]

EAU TV: Robotic surgery and advanced prostate cancer at EAU21

Prof. Albersen (BE) hosts this edition of EAU TV, welcoming Profs. Mottrie (BE), Fizazi (FR) and Gillessen (CH) to discuss today’s plenary sessions. Topics include suitable applications for robotic surgery, the VISION study and treatment sequencing in metastatic prostate cancer. This article was first published here. The post EAU TV: Robotic surgery and advanced prostate […]

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