EAU 2021: DANUBE Post-Hoc Analysis: Outcomes for Durvalumab with or Without Tremelimumab by Cisplatin Eligibility and PD-L1 Biomarker Status in Metastatic Urothelial Carcinoma

(UroToday.com) In this session, Dr. Thomas Powles provides an exploratory analysis of the DANUBE trial, with a focus on the outcomes of durvalumab (Durva) with or without tremelimumab (Treme) stratified by cisplatin eligibility and PD-L1 biomarker status in metastatic urothelial carcinoma (mUC). Dr. De Santis follows this discussion of the data and provides clinical context.

EAU 2021: Confederación Americana De Urología Lecture: What Is the Role of TUR in Muscle Invasive Bladder Cancer?

(UroToday.com) The 2021 European Association of Urology (EAU) Annual meeting’s Confederación Americana de Urología lecture was provided by Dr. Alejandro R. Rodriguez discussing the role of TUR in muscle invasive bladder cancer (MIBC). Dr. Rodriguez started by highlighting that bladder cancer is the 10th most commonly diagnosed cancer worldwide with 573,000 new cases and 213,000 deaths. […]

EAU 2021: State-of-the-Art Lecture: Does Every Metastatic Patient Need Immunotherapy in a First-Line Setting?

(UroToday.com) Dr. Enrique Grande from Madrid, Spain provided a state-of-the-art lecture at the European Association of Urology (EAU) 2021 annual meeting’s advanced bladder cancer session discussing immunotherapy in the first-line setting for metastatic bladder cancer. Dr. Grande notes that over the last several years, it seems that immunotherapy covers the entire spectrum of first-line treatment of […]

EAU 2021: Is There A Role For Neoadjuvant Immunotherapy In Muscle Invasive Bladder Cancer?

(UroToday.com)  The advanced bladder cancer in 2021 session of the European Association of Urology annual meeting included a presentation by Dr. Francois Audenet discussing the role of neoadjuvant immunotherapy in muscle-invasive bladder cancer (MIBC). Cisplatin-based chemotherapy before radical cystectomy is the gold standard for localized MIBC, given that it improves overall survival by 5% and […]

EAU 2021: State-of-the-Art Lecture: Safe and Optimal Management of MIBC in the Time of SARS-COV-2

(UroToday.com) Professor James Catto discussed the safe and optimal management of muscle-invasive bladder cancer (MIBC) in the time of COVID-19 pandemic at the European Association of Urology (EAU) 2021 virtual annual meeting’s plenary session on advanced bladder cancer. Based on data from the COVID-19 dashboard at Johns Hopkins University from June 15, 2021, the COVID-19 pandemic […]

EAU 2021: Pembrolizumab vs. Placebo as Post Nephrectomy Adjuvant Therapy for Patients with RCC: Randomized, Double-Blind, Phase 3 KEYNOTE-564 Study

(UroToday.com) At the 2021 European Association of Urology annual meeting Game Changing session, Dr. Tom Powles presented results of the KEYNOTE-564 trial evaluating pembrolizumab versus placebo as adjuvant therapy for patients with RCC. In 2018, kidney cancer was responsible for 175,000 deaths worldwide. Nephrectomy is the standard of care treatment for locoregional RCC, however, there is […]

X