Integrating Molecular Imaging Into Urologic Oncology Clinical Practice: Current Approaches and Future Opportunities- Risk Stratification of Localized Renal Tumors With Molecular Imaging

(UroToday.com) In anticipation of the 2021 American Urological Association Annual Meeting which is being held, in a delayed fashion, in September, the AUA is hosting both a “May Kick-Off Weekend” and “Summer School” which are highlighting a variety of important topics in both benign urology and urologic oncology. On June 15th, 2021, Dr. Marc Bjurlin, […]

Integrating Molecular Imaging Into Urologic Oncology Clinical Practice: Current Approaches and Future Opportunities- The Role of PSMA-PET in Prostate Cancer

(UroToday.com) In anticipation of the 2021 American Urological Association Annual Meeting which is being held, in a delayed fashion, in September, the AUA is hosting both a “May Kick-Off Weekend” and “Summer School” which are highlighting a variety of important topics in both benign urology and urologic oncology. On June 15th, 2021, Dr. Marc Bjurlin, […]

Proteomic Biomarkers for Urothelial Cancer Based on the Tissue Preservation Methods – Expert Commentary

Two key methods to preserve tumor tissues in biobanks are broadly adopted: formalin-fixation and paraffin-embedding (FFPE) and optimal cutting-temperature compound (OCT)- embedding and subsequent freezing, of the tissue specimens. Multiple proteins can be quantified simultaneously from the same sample using mass spectrometry (MS). However, applying MS to FFPE and OCT samples carries several technical challenges […]

FDA Grants Breakthrough Therapy Designation for Investigational 177Lu-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer (mCRPC)

San Francisco, CA (UroToday.com) — Novartis announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy designation (BTD) to 177Lu-PSMA-617, an investigational radioligand therapy for the treatment of metastatic castration-resistant prostate cancer (mCRPC).  Breakthrough Therapy designation is granted to medicines being evaluated for serious conditions where early clinical evidence indicates the potential for substantial […]

Overall Survival of Men with Metachronous Metastatic Hormone-Sensitive Prostate Cancer Treated with Enzalutamide and Androgen Deprivation Therapy – Beyond the Abstract

Evidence has been presented in the last seven years that has transformed the management of metastatic hormone-sensitive prostate cancer (mHSPC). The principles of management for about seven decades had fundamentally been around testosterone suppression. We now have clear data for the benefit of docetaxel (CHAARTED, STAMPEDE), abiraterone (LATITUDE, STAMPEDE), apalutamide (TITAN), and enzalutamide (ARCHES, ENZAMET).

Does Reduced Renal Function Predispose to Cancer-specific Mortality from Renal Cell Carcinoma? – Beyond the Abstract

The arguments in favor of partial nephrectomy (PN) over radical nephrectomy (RN) for patients with localized renal cell carcinoma (RCC) have been diverse and compelling,1 leading many to advocate for PN whenever feasible, even for potentially aggressive tumors.2 However, some patients with tumors with increased oncologic potential and/or high complexity may not be well-served by […]

X