ASCO 2021: Do Our Treatments Drive a New Resistant Mutational Phenotype?

(UroToday.com) In the plenary program of the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, Dr. Ana Aparicio discussed the potential for currently utilized treatments in advanced prostate cancer to drive a new resistant mutational phenotype within a session entitled “Beyond the Androgen Receptor: New Avengers in the Treatment of Castrate-Resistant Metastatic Cancer.”

ASCO 2021: A Randomized Phase II Study Comparing Cisplatin and Gemcitabine with or Without Berzosertib in Patients with Advanced Urothelial Carcinoma

(UroToday.com) Cisplatin and gemcitabine is a first line chemotherapy option for patients with metastatic urothelial carcinoma who are medically eligible to receive cisplatin. These chemotherapies induced DNA damage through distinct mechanisms, and it stands to reason that further disruption of DNA break repair may augment the efficacy of these agents. As the ATR (ataxia telangiectasia and […]

ASCO 2021: Disparities in Prostate Cancer: Are We Making Progress?

(UroToday.com) Following three presentations regarding various aspects of prostate cancer care with a focus on African American men in the Prostate, Testicular, and Penile Oral Abstract session at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, Dr. Peter Black summarized these data and considered the question of whether we are improving the known racial disparities […]

A bicentric retrospective analysis of clinical utility of 18F-fluciclovine PET in biochemically recurrent prostate cancer following primary radiation therapy: is it helpful in patients with a PSA rise less than the Phoenix criteria?

18F-Fluciclovine PET imaging has been increasingly used in the restaging of prostate cancer patients with biochemical recurrence (BCR); however, its clinical utility in patients with low prostate-specific antigen (PSA) levels following primary radiation therapy has not been well-studied.

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