ESOU 2022: New Tools for the Conservative Management of Upper Tract Urothelial Carcinoma

(UroToday.com) In a podium presentation in the Renal Cancer I – Localized session at the 19th Meeting of the EAU Section of Oncological Urology, Dr. Giusti presented on advances in conservative treatment approaches in patients with upper tract urothelial carcinoma (UTUC). He began by emphasizing that conservative treatment should be preferred for patients with low-grade disease […]

ESOU 2022: How MRI Changed the Bladder Cancer Pathway: New Evidence

(UroToday.com) The 2022 EAU Section of Oncological Urology (ESOU) Annual Meeting included a session on urothelial cancer and a presentation by Dr. Valeria Panebianco discussing how magnetic resonance imaging (MRI) has changed the bladder cancer pathway. Dr. Panebianco notes that for more than 30 years the diagnostic pathways for bladder cancer patients have remained largely unchanged, […]

ESOU 2022: 3D Augmented Reality in Robotic Assisted Partial Nephrectomy – What’s Next?

(UroToday.com) In a podium presentation in the Renal Cancer I – Localized session at the 19th Meeting of the EAU Section of Oncological Urology, Dr. Porpiglia presented on the role of augmented reality in robotic assisted partial nephrectomy. He began by defining, in this context, augmented reality as the superimposition of 3-dimensional (3D) virtual models over […]

ESOU 2022: State-of-the-art Lecture: Molecular Advances in Risk Stratification of Localized Prostate Cancer

(UroToday.com) The 2022 EAU Section of Oncological Urology (ESOU) Annual Meeting included a session on localized prostate cancer and a state-of-the-art lecture by Dr. Daniel Spratt discussing molecular advances in risk stratification of localized disease. Dr. Spratt notes that treatment decisions at their core are dominated by risk stratification, with the earliest risk stratification dating back […]

Epigenetic Priming of Bladder Cancer Cells With Decitabine Increases Cytotoxicity of Human EGFR and CD44v6 CAR Engineered T-Cells.

Treatment of B-cell malignancies with CD19-directed chimeric antigen receptor (CAR) T-cells marked a new era in immunotherapy, which yet has to be successfully adopted to solid cancers. Epigenetic inhibitors of DNA methyltransferases (DNMTi) and histone deacetylases (HDACi) can induce broad changes in gene expression of malignant cells, thus making these inhibitors interesting combination partners for […]

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