ASCO 2021: Health-Related Quality of Life and Patient-Reported Outcomes at Final Analysis of the TITAN Study in Patients with Metastatic Castration-Sensitive Prostate Cancer

(UroToday.com)  One of the fastest moving disease spaces in prostate cancer in metastatic castration sensitive prostate cancer. While androgen-deprivation therapy (ADT) alone was the standard treatment five years ago, now there are a number of treatment options which have been shown to improve overall survival, including docetaxel, abiraterone acetate, enzalutamide, and apalutamide. TITAN was the […]

ASCO 2021: Immunogenic Priming with 177Lu-PSMA-617 Plus Pembrolizumab in Metastatic Castration-Resistant Prostate Cancer: A phase 1b study

(UroToday.com) There has been a proliferation in treatment options for patients with metastatic castration resistant prostate cancer (mCRPC) in the last 10 years. While the most commonly utilized approaches in prostate cancer are cytotoxic chemotherapy or target the androgen-axis, immune checkpoint inhibitors have revolutionized care of many solid organ malignancies. To data, immune checkpoint inhibitors have […]

ASCO 2021: PSMA-Targeted Imaging with 18F-DCFPyL-PET/CT in Patients with Biochemically Recurrent Prostate Cancer: A Phase 3 Study (CONDOR)—A Subanalysis of Correct Localization Rate and Positive Predictive Value by Standard of Truth

(UroToday.com) PSMA-targeted PET/CT is superior to conventional imaging modalities to localize biochemically recurrent prostate cancer after local therapy, particularly in patients with low PSA (< 2 ng/mL) values. However, few studies have reported PSMA-targeted PET/CT accuracy compared to a pre-specified rigorous standard of truth including histopathology, correlative imaging, or treatment response in this population. The previously […]

TRANSCRIPT: ASCO 2021: ODENZA – Karim Fazizi

Alicia Morgans: Hi, my name is Alicia Morgans and I’m a GU medical oncologist and associate professor of medicine at Northwestern University in Chicago in the United States. I’m so excited to have here with me today a good friend and colleague Dr. Karim Fizazi, who’s a GU medical oncologist and professor of oncology at […]

ASCO 2021: Medical Oncology Perspective: The Promise and Limitations of Precision Health in Metastatic Disease

(UroToday.com) The 2021 American Society of Clinical Oncology (ASCO) program included a session discussing the application of genomic testing treatments for patients with prostate cancer, including a presentation by Dr. Franklin Huang discussing the medical oncology perspective of the promise and limitations of precision health in metastatic disease.

New Study Results Presented by Foundation Medicine and Collaborators at ASCO21 on Ancestry-Based Disparities in Prostate Cancer Care Underscore Importance of Equitable Access to Precision Medicine Advances

Data sourced from clinico-genomic database revealed lower rates of early genomic testing use and clinical trial enrollment among men of African ancestry compared to those of European ancestry San Francisco, CA (UroToday.com) — Foundation Medicine, Inc. and its collaborators announced the presentation of new data analyzing the genomic landscape, comprehensive genomic profiling (CGP) utilization and treatment […]

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