For men choosing to screen for prostate cancer (PCa), biopsy remains critical for diagnosis. While transrectal ultrasound-guided (TRUS) biopsy has been the standard of care for many years, recent concerns regarding post-procedural infection have led to increased interest in prostatic sampling via the transperineal (TP) approach.
Active surveillance (AS) is an established approach in the management of low-risk, localized prostate cancer. While the use of AS to manage intermediate-risk (IR) disease has gradually increased over time, there remains uncertainty with regards to its safety, with only a minority of IR patients currently being managed with this approach.
To evaluate the influence of endogenous testosterone density (ETD) on pelvic lymph node invasion (PLNI) in high risk (HR) prostate cancer (PCa) treated with radical prostatectomy (RP) and staged with extended pelvic lymph node dissection (ePLND).
Prostate cancer (PCa) is a severe public health issue and the most common cancer worldwide in men. Early diagnosis can lead to early treatment and long-term survival. The addition of the multiparametric magnetic resonance imaging in combination with ultrasound (mpMRI-U/S fusion) biopsy to the existing diagnostic tools improved prostate cancer detection.
The Cancer of the Bladder Risk Assessment (COBRA) score is a predictive tool for estimating Cancer Specific Survival (CSS) after Radical Cystectomy (RC) for urothelial carcinoma. COBRA score variables are: age at RC, Tumor stage and Lymph Node Density (LND).
Lower extremity lymphedema is a major source of morbidity in up to 70% of penile cancer patients. Lymphedema is often thought to be incurable, though surgical treatments have started to emerge. This study is the first to apply lymphovenous bypass specifically to penile cancer patients status post lymphadenectomy.
To evaluate long-term renal function in patients with CKD IIIa who underwent radical cystectomy and orthotopic neobladder (RC/ONB) compared to matched controls. Using our IRB-approved institutional database, patients with glomerular filtration rate (GFR) 45-59.
Squamous cell carcinoma of the urinary bladder associated with non-schistosomiasis (NSR-SCCUB) is an uncommon tumor subtype distinct from urothelial carcinoma (UC). NSR-SCCUB type is slightly more prevalent in men and is associated with chronic bladder irritation from chemotherapy, chronic bladder infections, or indwelling catheters. In addition, patients with these tumors tend to have a higher […]
{{header-clinical-trials-navigation}} Open-label Study of Androgen Receptor Inhibition With dArolutamide Plus Androgen Deprivation Therapy (ADT) Versus ADT in Men With Metastatic Hormone-Sensitive Prostate Cancer Using an External Control Arm Condition: Metastatic Hormone-sensitive Prostate Cancer Study Type: Interventional Clinical Trials Identifier NCT 8-digits: NCT05059236 Sponsor: Bayer Phase: Phase 2 Eligibility: Age: minimum 18 Years maximum N/A Gender: […]
Genetic alterations involving NF2 occur at low frequencies in renal cell carcinoma across all of the major histologic subtypes and have been associated with adverse outcomes. To better characterize tumors harboring these alterations, we identified 14 cases with NF2 mutations that had been previously diagnosed as papillary renal cell carcinoma; renal cell carcinoma, unclassified; or […]
