Clear cell renal cell carcinoma (ccRCC) represents 85% of kidney cancers and 3% of adult cancers. If diagnosed early, the main treatment is surgery. However, approximately 40% develop metastatic disease.
This molecular tumor board is a rare example of having complete whole-genome sequencing data from the germline and tumor in a living patient facing aggressive prostate cancer in real-time. We provide a case report of how our multidisciplinary team of medical oncologists, pathologists, cancer biologists, and bioinformatics specialists thinks through the complexities of this big […]
Abiraterone acetate has demonstrated benefit across the metastatic prostate cancer spectrum when combined or layered on conventional androgen deprivation therapy. Whether it be metastatic castration-sensitive (mCSPC) or metastatic castration-resistant prostate cancer (mCRPC) in either the pre-or the post-docetaxel setting, the overall survival benefit is certain.1-4 Attempts to advance to the next level with additional agents […]
To assess the literature around post-treatment asymptomatic residual stone fragments, and to perform a meta-analysis. The main outcomes were intervention rate and disease progression. We searched Ovid Medline, Embase, Cochrane library and Clinicaltrials.
Low-dose computer tomography (NCCT) is the standard imaging modality for patients with acute flank pain with a suspicion of urolithiasis. The stone size is usually measured 2D by a radiologist. We compared 3D stone measurement using different windows to the 2D measurement and evaluated the clinical impact on ureterorenoscopic stone removal (URS).
To review the available evidence regarding health disparities in kidney stone disease and identify knowledge gaps in this area. A literature search was conducted using PubMed, Embase, and Scopus, limited to articles published in English, from 1971 to 2020.
The disproportionate costs of state-of-the-art endoscopic equipment prohibit urologists from performing endoscopy in underserved countries. Given the global prevalence of smartphones, we engineered a $45 alternative endoscope utilizing three-dimensional (3D) printed attachments, an 8x lens, and a 1,000-lumen light-emitting diode (LED) cordless flashlight (Endockscope System (ES)).
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most frequent form of prostatitis, and has a serious impact on patients’ quality of life, and causes severe symptoms. The pain in the pelvic, perineal and penile areas, lower abdominal pain, and pain during urination or ejaculation are the main complaints of CP/CPPS.
Despite encouraging results, the optimal low-intensity shockwave therapy (LiST) protocol in patients with chronic prostatitis/chronic pelvic pain syndrome (CPPS) remains unknown. We conducted a two-arm, parallel-group, randomized controlled trial aiming to compare the efficacy and safety of six LiST sessions applied once or twice weekly.
Semen analysis (spermiogram) is a crucial component of the diagnostic work-up of infertile patients, in cases of cryopreservation of semen for fertility protection prior to potentially gonadotoxic treatment or for the assessment of sperm quality for sperm donation.
