Accurate identification of ideal candidates for cytoreductive nephrectomy (CN) for metastatic renal cell carcinoma (mRCC) is an unmet need. We tested the association between preoperative value of systemic albumin to globulin ratio (AGR) and overall survival (OS) as well as cancer-specific survival (CSS) in mRCC patients treated with CN.
The aim of this study was to describe pathologic and short-term oncologic outcomes among Black and White men with grade group 4 or 5 prostate cancer managed primarily by radical prostatectomy. This was a multi-institutional, observational study (2005-2015) evaluating radical prostatectomy outcomes by self-identified race.
An accurate and early diagnosis of bladder cancer (BC) is essential to offer patients the most appropriate treatment and the highest cure rate. For this reason, patients need to be best stratified by class and risk factors.
The use of immune checkpoint blockade, in particular PD-1 and PD-L1 inhibitors, is now commonplace in many clinical settings including the treatment of muscle-invasive bladder cancer (MIBC). Notwithstanding, little information exists regarding the expression of the alternative PD-1 ligand, PD-L2 in urothelial bladder cancer (UBC).
Radiotherapy has an important role in the curative and palliative treatment settings for bladder cancer. As a target for radiotherapy the bladder presents a number of technical challenges. These include poor tumor visualization and the variability in bladder size and position both between and during treatment delivery.
The use of Pembrolizumab has been largely accepted in several advanced types of cancers. PURE 01 study (NCT02736266) enrolled consecutively 143 patients with muscle-invasive bladder cancer who received 3 cycles of pembrolizumab 200 mg every 3 weeks before planned radical cystectomy (RC).
(UroToday.com) A urinary tract infection (UTI) is defined as microbial infiltration of the normally sterile urinary tract. But there are no accepted definitions of UTI-associated symptoms, cut-offs for culture result, or definitively accepted uropathogens that can guide clinicians in the objective management of a UTI. Urine is no longer considered sterile as microbes reside within the […]
Christopher Wallis: Hello, and welcome to this UroToday Journal Club. Today we’re discussing a recently published review paper entitled Androgen receptor inhibitor treatments: cardiovascular adverse events and comorbidity considerations in patients with non-metastatic prostate cancer. I’m Chris Wallis, a Fellow in Urologic Oncology at Vanderbilt, and with me is Zach Klaassen, an assistant professor in urology […]
(UroToday.com) Vaginal laser therapy is a thermal therapy. There are three main types of vaginal laser: Functionated CO2 (Femlift Alma, MonaLisa Touch) Radiofrequency (ThermaVa, ReVivie, Venus Fuiore, Viveve System, Protégé Intima, Pelleve, Ellma) Er:YAG (IntimasLase, Petit Lady Lutronic)
(UroToday.com) Dr Rovner moderated a symposium on Bulkamid®, a periurethral injection which was approved by the FDA in 2020 for the treatment of stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (ISD) or in women who have SUI or stress predominant mixed urinary incontinence (UI). It is now the leading bulking agent in Europe, Australia, and […]
