TRANSCRIPT: ASCO GU 2021 Benjamin Maughan – Randomized Phase II Trial of Radium-223 plus Enzalutamide versus EZ Alone in mCRPC

Chuck Ryan: Hi, I’m Chuck Ryan from the University of Minnesota, and I’m delighted today to be joined by Benjamin Maughan, who is an assistant professor at the University of Utah’s Huntsman Cancer Institute, where he is a member of the GU oncology program there. They presented recently a phase II study of radium-223 plus […]

TRANSCRIPT: ASCO GU 21 TPS503 Dickon Hayne SUBDUE-1

Ashish Kamat: Hello, and welcome to UroToday’s Bladder Cancer Center of Excellence. I’m Ashish Kamat, professor of urologic oncology at MD Anderson Cancer Center in Houston, Texas. And it’s my pleasure today to welcome Professor Hayne, all the way from Australia. Professor Hayne is joining us. He is a professor of urology at UWA and […]

Current Knowledge on Genomic Profiling of Upper Tract Urothelial Carcinoma.

Recent research in next-generation sequencing characterized the genomic landscape of urothelial cancer. However, the majority of the studies focused on bladder cancer (BC). Upper urinary tract urothelial carcinomas (UTUC) and BC share some histological characteristics, but, considering the differences in terms of embryologic precursors, epidemiology, genetics, medical and surgical management and response to therapy, UTUC […]

Molecular correlates of response to nivolumab at baseline and on treatment in patients with RCC.

Nivolumab is an immune checkpoint inhibitor targeting the programmed death-1 receptor that improves survival in a subset of patients with clear cell renal cell carcinoma (ccRCC). In contrast to other tumor types that respond to immunotherapy, factors such as programmed death ligand-1 (PD-L1) status and tumor mutational burden show limited predictive utility in ccRCC.

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