Our objective was to establish the incidence of positive surgical margins, recurrence patterns, recurrence free (RFS) and overall survival (OS) in a large cohort of patients undergoing robotic (RARC) and open radical cystectomy (ORC).
To determine whether repeated FDG-PET-CT-scans can predict increased disease-specific survival after induction chemotherapy followed by radical cystectomy. Between 2007 and 2018, 86 patients with clinically node-positive bladder cancer (T1-T4, N1-N3, M0-M1a) were included and underwent a repeated FDG-PET-CT during cisplatin-based induction chemotherapy.
To evaluate the risk of residual tumor and tumor upstaging during a second resection after primary complete Transurethral Resection of Bladder Tumor (TURBT) using Photodynamic Diagnosis (PDD) for high-risk Non-Muscle Invasive Bladder Cancer (NMIBC).
The ability to predict clinical outcomes prior to starting therapy is the hallmark of precision oncology. The detection of the androgen receptor splice variant 7 (AR-V7) in circulating tumor cells (CTCs) has now been externally and prospectively validated in the multicenter PROPHECY study using both the Hopkins mRNA and the Epic Sciences nuclear protein assays, […]
Background – Androgen receptor (AR) signaling inhibitors represent the standard treatment in metastatic castration resistance prostate cancer (mCRPC) patients. However, some patients display a primary resistance, and several studies investigated the role of the AR as a predictive biomarker of response to treatment. This study is aimed to evaluate the role of AR in liquid […]
It’s now been 3.5 years since I last wrote anything about testicular germ cell tumors and ongoing clinical trials.1 Although we still cure most men afflicted with this disease, we have not made any major new therapeutic advancements since I wrote that last article. Approximately, 15-20% of patients with metastatic germ cell tumors will relapse following […]
While we all had long hoped to have our Annual Congress in Milan this year, we feel there is currently insufficient scope for a successful congress in Italy this summer. With too many uncertainties about the current situation, we feel that we can best serve our members and congress delegates with an online-only EAU21 Virtual Congress. […]
Although miniaturized percutaneous nephrolithotomy (mPCNL) and retrograde intrarenal surgery (RIRS) are both options for treating >1cm kidney stones, controversies exist on whether one is more effective and safer than the other.
Despite being recommended by most guidelines, the metabolic evaluation of patients with nephrolithiasis has limited diffusion due to difficulties relating both to the access to laboratory investigations and to urine collection modalities.
To assess the impact of interactions between kidney stone formation and conventional risk factors on incident chronic kidney disease (CKD). A total of 11,402 subjects (men 30-69 years of age, Japanese) without CKD at baseline were observed over an average period of 4 years.
