Latest News

(UroToday.com) Enfortumab vedotin is an antibody-drug conjugate targeting Nectin-4 (encoded by the PVRL4/NECTIN4 gene) approved for treatment-refractory metastatic urothelial cancer based on several studies.1-3 EV-201 represented a heavily pre-treated population with a 44% overall response rate, 12% complete response rate, 7.6-month median duration of response, 11.7-month median overall survival, and 5.8-month progression-free survival.2 However, factors that mediate sensitivity or […]

(UroToday.com) The renal cell carcinoma session at the GU ASCO 2021 annual meeting included a ‘Best of the Journals’ session with Dr. Bimal Bhindi presenting impactful papers from the surgical perspective. Dr. Bhindi’s objective was to highlight the most practice influencing papers on kidney cancer surgery in the last year, performing a systematic PubMed search from […]

(UroToday.com) The renal cell carcinoma session at the GU ASCO 2021 annual meeting included a ‘Best of the Journals’ session with Dr. Eva Comperat presenting impactful papers from the pathology perspective.

(UroToday.com) Survival after orchiectomy in stage I seminoma is almost 100% and the use of CT surveillance is an international standard of care, avoiding adjuvant therapy. In this young population, who are unlikely to die from testicular cancer, minimizing irradiation is vital. The Trial of Imaging and Surveillance in Seminoma Testis (TRISST, NCT00589537), assessed whether CTs […]

The distribution of metastatic sites in upper tract urothelial carcinoma (UTUC) is not well-known. Consequently, the effects of sex and age on the location of metastases is also unknown. This study sought to investigate age- and sex-related differences in the distribution of metastases in patients with UTUC.

Testicular cancer (TC) survivors have an increased risk of various second primary malignancies. A recent cohort study detected an increased risk of colorectal cancer (CRC) in TC survivors treated with platinum-based chemotherapy with a hazard ratio of 3.

Metabolic rearrangement is a marker of cancer that has been widely studied in recent years. One of the major metabolic characteristics of tumor cells is the high levels of glycolysis, even under aerobic conditions, a phenomenon that is called the "Warburg effect.

(1) Background: Renal cancer is one of the most frequent malignancies in Western countries, with an unpredictable clinical outcome, partly due to its high heterogeneity and the scarcity of reliable biomarkers of tumour progression.

The present study examined the prevalence of changes in the taste and smell of food among men with advanced prostate cancer who were receiving hormone therapy and/or chemotherapy. Participants were 75 men with advanced prostate cancer treated at an academic medical center.

The prognosis and optimal management of pN0/pN1 patients with persistently elevated prostate-specific antigen (PSA) 6-8 wk after radical prostatectomy (RP) remain unclear. To perform a systematic review of oncologic outcomes and effectiveness of salvage therapies in men with a detectable PSA level after RP.