Janssen Announces Treatment with Apalutamide Significantly Improved Overall Survival in Patients with Metastatic Castration-Sensitive Prostate Cancer

Final analysis from Phase 3 TITAN study demonstrated ERLEADA® provided statistically significant overall survival benefit and consistent safety profile in patients with advanced prostate cancer, regardless of extent of disease San Francisco, CA (UroToday.com) — The Janssen Pharmaceutical Companies of Johnson & Johnson announced results from the final analysis of the Phase 3 TITAN study, which […]

Increase in Metastatic Prostate Cancer Diagnoses Seen After Reduction in PSA Screening in United States

ASCO Perspective “This study suggests that reduced PSA screening may come at the cost of more men presenting with metastatic prostate cancer. Patients should discuss the risks and benefits associated with PSA screening with their doctor to identify the best approach for them,” said Robert Dreicer, MD, MS, MACP, FASCO, ASCO expert in genitourinary cancers.

Immunotherapy Nivolumab Doubles Disease-Free Survival in a Type of High-Risk Urothelial Carcinoma

ASCO Perspective “Even with the current standard of care — surgery with or without pre-surgery chemotherapy —muscle-invasive urothelial carcinoma has a high risk of recurring. These new findings show that treating patients at highest risk of recurrence with an immunotherapy after surgery can help extend the time until the disease returns,” said Robert Dreicer, MD, […]

Comparison of Multiparametric Magnetic Resonance Imaging–Targeted Biopsy With Systematic Transrectal Ultrasonography Biopsy for Biopsy-Naive Men at Risk for Prostate Cancer: A Phase 3 Randomized Clinical Trial

Key Points Question: Is magnetic resonance imaging (MRI) with targeted biopsy only non-inferior to systematic biopsy for the diagnosis of clinically significant prostate cancer (PCa)? Findings: In this prospective phase 3 randomized clinical trial of 453 men, clinically significant cancer was found in 35% vs 30% in the MRI and systematic biopsy arms, respectively, which […]

Blue Earth Diagnostics Highlights Presentations on Fluciclovine F 18 at Upcoming 2021 ASCO Genitourinary Cancers Symposium

San Francisco, CA (UroToday.com) — Blue Earth Diagnostics, a Bracco company and recognized leader in the development and commercialization of innovative PET radiopharmaceuticals, announced presentations on Axumin® (fluciclovine F 18) at the upcoming ASCO 2021 Genitourinary Cancers Symposium (ASCO GU), from February 11 to 13, 2021, to be held in a virtual format. Details of selected […]

Bayer and Orion Expand Development Program for Darolutamide in Prostate Cancer

Phase III study ARANOTE to be initiated in metastatic hormone-sensitive prostate cancer (mHSPC) assessing the androgen receptor inhibitor (ARi) in combination with standard androgen deprivation therapy (ADT) Start of patient enrollment expected by the end of Q1 2021 Study adds to the robust development program for NUBEQA, exploring an opportunity to help even more patients […]

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