Delaying BCG immunotherapy onset after transurethral resection of non-muscle-invasive bladder cancer is associated with adverse survival outcomes.

This study was carried out to assess whether a prolonged time between primary transurethral resection of non-muscle-invasive bladder cancer (TURB) and implementation of bacillus Calmette-Guerin (BCG) immunotherapy (time to BCG; TTBCG) is associated with adverse oncological survival in patients with T1 high-grade (HG) non-muscle-invasive bladder cancer (NMIBC).

Efficacy and Safety of Nivolumab Plus Ipilimumab versus Sunitinib in First-Line Treatment of Patients with Advanced Sarcomatoid Renal Cell Carcinoma – Beyond the Abstract

Renal cell carcinoma (RCC) with sarcomatoid features (sRCC) is an aggressive cancer that comprises approximately 5% of all RCC patients, including an estimated 10%-20% of patients with advanced disease.1-3 Although the presence of sarcomatoid features is known to be an independent predictor of poor survival, previous clinical trial data assessing the role of immunotherapy in […]

New Data Analyses from Phase 3 Study of Investigational Gene Therapy Nadofaragene Firadenovec Presented at Society of Urologic Oncology Annual Meeting Adds More Evidence to Data Published in Lancet Oncology

Low rate of cystectomy and delayed time to cystectomy among patients who achieved complete response Patient characteristics or prior treatment history do not influence response Significant anti-adenovirus antibody response does not appear to affect patient outcomes San Francisco, CA (UroToday.com) — FerGene Inc. announced new data analyses results from the landmark Phase 3 clinical trial evaluating […]

Targeted Alpha Therapy in mCRPC (Metastatic Castration-Resistant Prostate Cancer) Patients: Predictive Dosimetry and Toxicity Modeling of 225Ac-PSMA (Prostate-Specific Membrane Antigen).

Radioligand therapy is a type of internal radiotherapy combining a short-range radioisotope labeled to a carrier with a high affinity for a specific receptor expressed on tumor cells. Targeted alpha therapy (TAT) combines a high-linear energy transfer (LET) emitter (225Ac) with a prostate-specific membrane antigen (PSMA) carrier, specifically binding tumor cells in patients with metastatic […]

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