In this study, we constructed a model using a Cox proportional hazards model based on the expression of eight immune-related genes that were associated with prognosis in prostate cancer: EDNRB, ANGPTL2, TNFSF15, TNFRSF10D, EDN2, BMP2, NLRP14, and PLK1.
Clinical trial evidence has affirmed the role for immuno-oncology (IO) treatment for locally advanced or metastatic urothelial carcinoma (la/mUC). This Study informing treatment Pathway dEcision in bladder cAnceR (SPEAR-Bladder) aimed to provide insight into the optimal sequencing of IO treatments among la/mUC patients treated in the US Oncology Network.
The long noncoding RNA cancer susceptibility candidate 9 (CASC9) has been revealed to be an oncogenic gene in several types of cancer, and high CASC9 expression is related to tumorigenesis and cancer progression.
Robot-assisted radical cystectomy (RARC) with intracorporeal neobladder formation is a complex surgical procedure. To describe the main stages of RARC and to analyze its short-term results. RARC with ileocystoplasty was performed in 16 patients, most of whom were men (n=14).
Bladder cancer is a common malignancy in women and is the fourth most common malignancy in men. Bladder cancer ranges from unaggressive and usually noninvasive tumors that recur and commit patients to long-term invasive surveillance, to aggressive and invasive tumors with high disease-specific mortality.
Extension study demonstrates favorable results in long term treatment of overactive bladder with vibegron, including improvements in incontinence efficacy, quality of life endpoints, and with good tolerability Long term EMPOWUR extension study data featured in an oral presentation at the virtual International Continence Society (ICS) Annual Meeting Meta-analysis on increased risk of incident dementia following the use […]
Serum levels of microRNA-371a-3p (M371) have been shown to be a highly sensitive and specific biomarker for testicular germ cell tumours (TGCT). Little information exists on the expression of this marker in testicular neoplasms deriving from the gonadal stroma or other structures of the gonad.
To assess the feasibility of Robot-assisted Radical nephrectomy with Inferior Vena Cava Thrombectomy (RRVCT) and compare peri operative and oncological outcomes of this approach to open surgery for renal tumors with Level 1-2 Inferior Vena Cava (IVC) Thrombus.
The role of robot-assisted partial nephrectomy (RAPN) in the management of renal masses has exponentially grown over the past 10 years. Nevertheless, data on long term outcomes of the procedure remains limited.
Men with low risk prostate cancer on active surveillance undergo multiple biopsies over time. The long-term clinical significance of consecutively negative biopsies is not known. Men with low risk prostate cancer prospectively enrolled in an active surveillance database with at least 4 biopsies were included in the study.
