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Ureteroscopy (URS) and percutaneous nephrolithotomy (PCNL) are two surgical treatment options for the management of intermediate-size (15-20mm) kidney stones. Given there are differences between these two procedures in surgical technique, stone-free rates, and complication risks to name a few distinctions, physician to patient counseling often plays an important role in the shared decision-making process before […]

Alicia Morgans:  Hi, my name is Alicia Morgans and I am a GU Medical Oncologist at Northwestern University in Chicago, Illinois. I am so excited to have here with me today Dr. Phil Spiess, who is a Professor of Oncology and Urology at Moffitt Cancer Center in Florida, where he is also the Assistant Chief […]

Senior Author:  Ash Tewari, MBBS, MCh, Chair of the Department of Urology at the Mount Sinai Health System, Professor, Urology, Oncological Sciences, Icahn School of Medicine at Mount Sinai First Author:  Vinayak G Wagaskar, MBBS, MCh, Clinical Fellow, Department of Urology Icahn School of Medicine at Mount Sinai Bottom Line: This study described a novel surgical […]

Background A common side effect following radical prostatectomy is urinary incontinence. Here, we describe a novel surgical technique to reduce postoperative urinary incontinence and facilitate early return of continence. Objective To describe the novel “hood technique” for robotic-assisted radical prostatectomy (RARP). Design, setting, and participants This is an institutional review board–approved prospective study of 300 […]

{{header-clinical-trials-navigation}} Treatment Of Metastatic Bladder Cancer at the Time Of Biochemical reLApse Following Radical Cystectomy Condition: Bladder Cancer, Bladder Cancer, Metastatic Study Type: Interventional Clinical Trials Identifier NCT 8-digits: NCT04138628 Sponsor: Jørgen Bjerggaard Jensen Phase: Phase 2 Eligibility: Age: minimum 18 Years maximum N/A Gender: All Inclusion Criteria: ≥18 years of age at the time […]

The presence of histologically different neoplasms in the same organ is rare in pathologic practice. We report the first case of synchronous clear cell renal cell carcinoma (clear cell RCC) and papillary renal neoplasm with reverse polarity (PRNRP) with comprehensive immunohistochemical and molecular characterization using next-generation sequencing (NGS).

To investigate the somatic mutation profiles of testicular germ cell tumors in Japanese men. We analyzed the somatic missense mutation profile of testicular germ cell tumors among 21 Japanese men with seminoma (n = 14), pure embryonic carcinoma (n = 3) and mixed testicular germ cell tumor (n = 4) by targeted next-generation sequencing of 409 cancer-related genes covering 1.

Although immune checkpoint inhibitors and targeted therapeutics have changed the landscape of treatment for renal cell carcinoma (RCC), most patients do not experience significant clinical benefits.

Metastasis of renal cell carcinoma to the oral cavity is rare. Renal cell carcinoma metastases are regarded as radioresistant tumors and surgery is recommended. However, since metastatic renal cell carcinoma has poor prognosis and is composed of abundant blood vessels, it is sometimes difficult for clinicians to choose surgical therapy.

The rapidly changing treatment landscape in metastatic castration-resistant prostate cancer (mCRPC) calls for biomarkers to guide treatment decisions. We recently identified MMP-7 as a potential serum marker for the prediction of response and survival in mCRPC patients who received docetaxel (DOC) chemotherapy.