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Interstitial cystitis/bladder pain syndrome (IC/BPS), which is characterized by bladder pain and irritative voiding symptoms, is a frustrating disease without effective treatment. The cause is still largely not understood, although urothelium ischemia/hypoxia, apoptosis, denudation, and infiltration of inflammatory cells are common histopathological findings.

The current study aimed to investigate the clinical significance of European Society for the Study of Interstitial Cystitis (ESSIC) bladder histopathological classification and its impact on treatment outcomes among patients with interstitial cystitis/bladder pain syndrome (IC/BPS).

Catheter-associated urinary tract infection (CAUTI) can significantly affect patients’ quality of life and increase healthcare costs. This study aimed to capture patients’ and nurses’ experience of catheter maintenance using a polyhexanide-based solution (PS) in everyday practice.

To assess the effectiveness of an intralesional injection of verapamil in men with Peyronie’s disease (PD). The data provided in the current review are based on a thorough review of the available original articles on PD retrieved with a systematic literature search using PubMed- Medline, and the Cochrane Central Register of Controlled Trials, up to […]

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a disease with diverse clinical manifestations, such as pelvic pain or perineal pain. Although recent studies found several risk factors related to the pain severity of CP/CPPS patients, results were inconsistent.

Providers may use several treatment options for patients with Peyronie’s disease; however, it is unclear whether practice patterns have evolved over recent years and if this has impacted cost. To investigate trends in the treatment of Peyronie’s disease over time and the associated costs using a national, commercial insurance claims database.

Male hypogonadotropic hypogonadism (MHH) is effectively treated by gonadotropins with a high rate of ejaculate sperm and paternity; however, there is no information regarding the appropriate management, including patient-reported outcomes (PROs), of men with MHH who have finished infertility treatment.

Controversy exists around the use of epididymal sperm for in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) for couples with obstructive azoospermia (OA), and the ability to reliably predict IVF/ICSI outcomes with surgically extracted epididymal sperm remains limited.

To assess if the effect of intracavernosal injection (ICI) of prostaglandin E1 (PGE1) on duration and rigidity of erection is dose dependent in patients with different types of vasculogenic erectile dysfunction (ED)? A hundred patients with ED were assigned into 4 groups (n=25/each); group (A) patients with arteriogenic ED, group (B) patients with veno-occlusive ED, […]

To describe the prevalence of Y-chromosome deletions in patients with a sperm concentration of less than five million/ml. To also determine a new sperm threshold for Y-chromosome analysis in men with infertility.