Evaluation of a 3-item screening tool to identify men with benign prostatic enlargement/obstruction in a primary care cohort.

Benign prostatic hyperplasia (BPH), a progressive condition and common cause of lower urinary tract symptoms (LUTS), is underdiagnosed in primary care, impacting patient outcomes. Here, we evaluate the utility of a BPH screening tool in general practice, to identify men confirmed to have BPH after urologist assessment of diagnostic test results.

Downstream Neighbor of SON (DONSON) Is Associated with Unfavorable Survival Across Diverse Cancers with Oncogenic Properties in Clear Cell Renal Cell Carcinoma – Beyond the Abstract

Our study aimed at identifying prognostically relevant genes as plausible targets for further research by using the comprehensive The Cancer Genome Atlas (TCGA) datasets.2 By performing systematic survival analyses across 30 different tumor entities, we discovered the so far widely unknown gene Downstream neighbor of SON (DONSON) gene to be a particularly strong predictor of […]

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