To assess the efficacy and safety of docetaxel rechallenge in the salvage setting in metastatic castration-resistant prostate cancer (mCRPC) patients. Clinicopathologic data from patients treated with docetaxel rechallenge were collected from a single-center cancer registry.
Histopathological examination of sentinel lymph nodes in penile cancer have varied over the first 10 years after introduction of the dynamic sentinel node (SLN) procedure in Denmark and guidelines have been sparse.
Intravesical BCG (Bacillus Calmette-Guérin) therapy is indicated as an effective treatment for patients with non-muscle-invasive bladder cancer, despite associate with the side effects. In this study, the incidence of BCG therapy adverse effects was compared among three groups of patients who received celecoxib, phenazopyridine, and oxybutynin with placebo.
Initial studies of preoperative checkpoint inhibition before radical cystectomy (RC) have shown promising pathologic complete responses. We aimed to analyze the survival outcomes of patients enrolled in PURE-01 study (NCT02736266).
RNA-binding proteins (RBPs) are a kind of gene regulatory factor that presents a significant biological effect in the initiation and development of various tumors, including bladder cancer (BLCA). However, the RBP-based prognosis signature for BLCA has not been investigated.
Previous studies have noted increased utilization of perioperative chemotherapy over time. The goal of this study was to determine trends in perioperative chemotherapy use within a contemporary population.
To clarify the potential therapeutic benefit of a second transurethral resection for high-grade Ta bladder cancer. From January 2009 to August 2019, 521 patients with bladder tumors underwent initial transurethral resection procedures at Kagawa University Hospital.
STUDY HIGHLIGHTS A KEY INTERACTION BETWEEN A CANCER DRUG AND THE GUT MICROBIOME THAT RESULTS IN BENEFICIAL ORGANISMS WITH ANTI-CANCER PROPERTIES Brendan Daisley, a PhD candidate at Western University’s Schulich School of Medicine & Dentistry, conducting research at Lawson Health Research Institute San Francisco, CA (UroToday.com) — A new study from Lawson Health Research Institute and Western University […]
Alicia Morgans: Hi, my name is Alicia Morgans and I am a GU Medical Oncologist and an Associate Professor at Northwestern University. I’m so excited to have here with me today, a friend and a colleague, Dr. Oliver Sartor, who is the Laborde Professor of Cancer Research, as well as being a professor of medicine […]
Abiraterone acetate (AA) is an inhibitor of androgen biosynthesis, though this cannot fully explain its efficacy against androgen-independent prostate cancer. Here, we demonstrate that androgen deprivation therapy depletes androgen-utilizing Corynebacterium spp.
