Benign prostatic hyperplasia (BPH) is a prevalent disease with significant health and economic impacts on individuals and health organisations across the world, whilst the cause/initiation of the disease process has still not been fully determined METHODS: This review presents historical and contemporary hypotheses on the pathogenesis of benign prostatic hyperplasia, with the potential implications in […]
Initial presentation of data from the Phase 1b part of the LIO-1 trial of lucitanib in combination with nivolumab in advanced metastatic solid tumors New data analyses for Rubraca® (rucaparib) from the Phase 2 TRITON2 and Phase 3 ARIEL3 studies in patients with metastatic castration-resistant prostate cancer (mCRPC) and recurrent ovarian cancer, respectively First presentation of […]
New study suggests that high-intensity focused ultrasound ablation is effective against prostate cancer with decreased side effects and improved recovery time. San Francisco, CA (UroToday.com) — For some prostate cancer patients, radical treatment (surgery or radiation) are treatment standards. However, these procedures may cause side effects including urinary incontinence or impotency.
San Francisco, CA (UroToday.com) — New research provides insights on the potential causes of racial disparities in deaths following prostate cancer surgery. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS).
To assess the impact of neoadjuvant chemotherapy (NAC) on survival outcomes in a contemporary cohort of patients with in upper tract urothelial carcinoma (UTUC). The National Cancer Data Base was queried from 2004-2015 to identify subjects who underwent nephroureterectomy for UTUC.
The use of organ sparing strategies to treat penile cancer (PC) is currently supported by evidence that has indicated the safety, efficacy and benefit of this surgery. However, radical penectomy still represents up to 15-20% of primary tumor treatments in PC patients.
To investigate the effect of down-regulation of pannexin 2 (Panx-2) channels on cisplatin-induced apoptosis in I-10 cells. The expression of Panx-2 protein in testicular cancer cells was detected with Western blotting.
Recently, the CARMENA and SURTIME studies, suggested that upfront cytoreductive nephrectomy (CN) should be abandoned for patients with intermediate and high-risk metastatic renal cell carcinoma (mRCC).
The coronavirus disease 2019 (COVID-19) pandemic necessitated rapid changes in medical practice. Many of these changes may add value to care, creating opportunities going forward. To provide an evidence-informed, expert-derived review of genitourinary cancer care moving forward following the initial COVID-19 pandemic.
Some reports showed encouraging efficacy of immune checkpoint inhibitors among patients who experienced immune-related adverse events (irAEs). Thus, characterization of T-cell repertoire and immune signatures in peripheral blood mononuclear cells (PBMCs) and tumors before and after immune checkpoint inhibitors treatment should contribute to better understanding of irAE-provoked anticancer immune responses.
